Triclosan (2,4,4′-trichloro-2′-hydroxydiphenyl ether) is a small lipophilic compound that has been used since about 1960 in cosmetics, disinfectants and other antibacterial products and it is easily absorbed through the skin.

Used in soaps and hand sanitizers.

Incorporated in products at concentrations between 0.1% and 1%.

Concerns about the use of this chemical component concerning allergies (1) and environmental hazards have emerged in countless specific studies.

Triclosan studies

Molecular Formula: C₁₂H₇Cl₃O₂

Molecular Weight: 289.536 g/mol

UNII: 4NM5039Y5X

CAS: 3380-34-5   112099-35-1  88032-08-0  164325-69-3  261921-78-2  1155174-27-8

EC Number: 222-182-2

FEMA Number:

Synonyms:

• 2,4,4'-Trichloro-2'-hydroxydiphenyl ether
• 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol
• Ether, 2'-hydroxy-2,4,4'-trichlorodiphenyl
• Phenyl ether, 2'-hydroxy-2,4,4'-trichloro-
• Cloxifenol
• 2-(2,4-dichlorophenoxy)-5-chlorophenol
• 2-Hydroxy-2',4,4'-trichlorodiphenyl Ether
• Irgasan
• Cloxifenolum
• Triclosanum
• Irgasan DP300
• Stri-Dex Face Wash
• Phenol, 5-chloro-2-(2,4-dichlorophenoxy)-
• Lexol 300
• trichloro-2'-hydroxydiphenyl ether
• 5-chloro-(2,4-dichlorophenoxy)phenor

References______________________________________

(1) Triclosan Induces Thymic Stromal Lymphopoietin in Skin Promoting Th2 Allergic Responses.
Marshall NB, Lukomska E, Long CM, Kashon ML, Sharpnack DD, Nayak AP, Anderson KL, Jean Meade B, Anderson SE.
Toxicol Sci. 2015 Sep;147(1):127-39. doi: 10.1093/toxsci/kfv113. Epub 2015 Jun 5.