Check the ingredients!
... live healthy!
|
|
|
|
| Donate | App | Join | Log in |
|
|
|
|
|
| Donate | App | Join | Log in |
 | "Butylphenyl Methylpropional studies" by AColumn (9309 pt) | 2020-Nov-04 09:34 |
| Evaluation | N. Experts | Evaluation | N. Experts |
|---|---|---|---|
| 1 | 6 | ||
| 2 | 7 | ||
| 3 | 8 | ||
| 4 | 9 | ||
| 5 | 10 |
Companies that place Butylphenyl Methylpropional (like many fragrances included in cosmetic products) in cosmetic products, must indicate the name on the label. In this way we report a chemical component for which a maximum reccomended dose (1).
In vitro estrogenic activity has been detected and an in vivo verification is needed to ascertain the extent to which Butylphenyl Methylpropional may enter human breast tissue and be absorbed through human skin (2).
It is a component used in deodorants and antiperspirants that could cause breast tumors (3).
better known as Lilial, which is discussed to cause contact dermatitis and induces dose-dependent toxicity, a decrease of cellular ATP content, and an increase of reactive oxygen species (ROS) production in HaCaT cells. (4)
References_________________________
(1) Preservatives and fragrances in selected consumer-available cosmetics and detergents.
Yazar K1, Johnsson S, Lind ML, Boman A, Lidén C.
Contact Dermatitis. 2011 May
(2) Charles AK, Darbre PD. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro.
Journal of Applied Toxicology. 2009
(3) Underarm antiperspirants/deodorants and breast cancer
Philippa D Darbre
Breast Cancer Res. 2009
Murawski A, Fiedler N, Schmied-Tobies MIH, Rucic E, Schwedler G, Stoeckelhuber M, Scherer G, Pluym N, Scherer M, Kolossa-Gehring M. Metabolites of the fragrance 2-(4-tert-butylbenzyl)propionaldehyde (lysmeral) in urine of children and adolescents in Germany - Human biomonitoring results of the German Environmental Survey 2014-2017 (GerES V). Int J Hyg Environ Health. 2020 Aug;229:113594. doi: 10.1016/j.ijheh.2020.113594.
(4) Geppert M, Schwarz A, Stangassinger LM, Wenger S, Wienerroither LM, Ess S, Duschl A, Himly M. Interactions of TiO2 Nanoparticles with Ingredients from Modern Lifestyle Products and Their Effects on Human Skin Cells. Chem Res Toxicol. 2020 May 18;33(5):1215-1225. doi: 10.1021/acs.chemrestox.9b00428. Epub 2020 Mar 5.
| Evaluate |
