Compendio degli studi più significativi con riferimento a proprietà, assunzione, effetti.

Mynenivenkatasatya SR, Wang H, Cooley W, Garcia-Smith E, Shewale J, Ratcliff J. Effectiveness of a Novel Dentifrice Containing Stabilized Chlorine Dioxide, Sarkosyl, and Sodium Fluoride. Dent J (Basel). 2020 Oct 27;8(4):122. doi: 10.3390/dj8040122.

Abstract. This in vitro study evaluated the effectiveness of a novel dentifrice containing stabilized chlorine dioxide, sodium lauroyl sarcosinate (sarkosyl), and sodium fluoride in enhancing enamel fluoride uptake, remineralization, pellicle cleaning and inhibiting biofilm regrowth. Remineralization was measured by fluoride uptake and surface microhardness assessment tests. 

Bajani D, Gharai D, Dey J. A comparison of the self-assembly behaviour of sodium N-lauroyl sarcosinate and sodium N-lauroyl glycinate surfactants in aqueous and aqueo-organic media. J Colloid Interface Sci. 2018 Nov 1;529:314-324. doi: 10.1016/j.jcis.2018.06.026.

Abstract.  The self-assembly properties of two NAAS, sodium N-lauroyl sarcosinate (SLS) and sodium N-lauroyl glycinate (SLG) that differ only in the head-group structure were compared in aqueous and aqueo-organic media by using a number of methods, including surface tension fluorescence, dynamic light scattering, calorimetry, and microscopy.

Rahman S, Arai S, Saijo S, Yamato I, Murata T. Sarkosyl is a good regeneration reagent for studies on vacuolar-type ATPase subunit interactions in Biacore experiments. Anal Biochem. 2011 Nov 15;418(2):301-3. doi: 10.1016/j.ab.2011.07.009.

Abstract.  Here we introduce the anionic detergent sodium lauroyl sarcosinate (sarkosyl), which works satisfactorily as a regeneration reagent. After regeneration by the mild detergent, the subsequent binding experiment was reproducible without any degradation of the ligand.

Long F, Cho W, Ishii Y. Expression and purification of 15N- and 13C-isotope labeled 40-residue human Alzheimer's β-amyloid peptide for NMR-based structural analysis. Protein Expr Purif. 2011 Sep;79(1):16-24. doi: 10.1016/j.pep.2011.05.012.

Abstract. This problem was resolved by efficient recovery of the GST-Aβ fusion protein from the inclusion bodies using 0.5% (w/v) sodium lauroyl sarcosinate as solubilizing agent and subsequent purification by affinity chromatography using a glutathione agarose column.

Chen Z, Liu J, Liang Y, Ren F. Use of sodium lauroyl sarcosinate in a high-sensitivity protein assay by resonance light scattering technique. J Biomol Screen. 2006 Jun;11(4):400-6. doi: 10.1177/1087057106286746.

Abstract. This method presented here is not only sensitive and simple but also reliable and suitable for practical bioassay applications.