Lysolecithin has been described as a powerful hemolytic. Furthermore, the toxic effect of many snake poisons is due to their content of phosphatidase A, an enzyme capable of converting plasma phosphat ...

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Lysolecithin has been described as a powerful hemolytic. Furthermore, the toxic effect of many snake poisons is due to their content of phosphatidase A, an enzyme capable of converting plasma phosphatides into lysophosphatides, one of which is Lysolecithin (1).

An intradermal injection of 0.04 micron to 0.25 micron of Lysolecithin derived from beef serum, human serum, gave reactions with bruise and erythema in the 3 subjects tested (2).

Apart from these allergies that can be traced back to subjectivity, Lysolecithin or Lysophosphatidylcholines, has shown efficacy in protecting human skeletal muscle cells from lipotoxicity (3).

Bibliografia______________________________

(1) Safety Assessment of Lecithin and Other Phosphoglycerides as Used in Cosmetics
 -  September 11, 2014

(2) Middleton, E. Jr. and Phillips G. B. Release of histamine activity in human skin by lysolecithin. Laboratory and
Clinical Medicine. 1964;64(6):889-894.

(3) Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity.
Klingler C, Zhao X, Adhikary T, Li J, Xu G, Häring HU, Schleicher E, Lehmann R, Weigert C.
Biochim Biophys Acta. 2016 Dec

(4) High-fat diet feeding differentially affects the development of inflammation in the central nervous system.
Guillemot-Legris O, Masquelier J, Everard A, Cani PD, Alhouayek M, Muccioli GG.
J Neuroinflammation. 2016 Aug

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