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Falcarinol
"Falcarinol studies"
by A_Partyns (12876 pt)
2019-Jun-08 20:22

Review Consensus: 8 Rating: 8 Number of users: 1
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Devil's Club Falcarinol-Type Polyacetylenes Inhibit Pancreatic Cancer Cell Proliferation.
Cheung SSC, Hasman D, Khelifi D, Tai J, Smith RW, Warnock GL.
Nutr Cancer. 2019;71(2):301-311. doi: 10.1080/01635581.2018.1559931.

Falcarinol Is a Potent Inducer of Heme Oxygenase-1 and Was More Effective than Sulforaphane in Attenuating Intestinal Inflammation at Diet-Achievable Doses.
Stefanson AL, Bakovic M.
Oxid Med Cell Longev. 2018 Oct 21;2018:3153527. doi: 10.1155/2018/3153527

Identification of Genes Encoding Enzymes Catalyzing the Early Steps of Carrot Polyacetylene Biosynthesis.
Busta L, Yim WC, LaBrant EW, Wang P, Grimes L, Malyszka K, Cushman JC, Santos P, Kosma DK, Cahoon EB.
Plant Physiol. 2018 Dec;178(4):1507-1521. doi: 10.1104/pp.18.01195.

Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer.
Kobaek-Larsen M, Nielsen DS, Kot W, Krych Ł, Christensen LP, Baatrup G.
BMC Res Notes. 2018 Jun 27;11(1):411. doi: 10.1186/s13104-018-3527-y.

Ameliorative effect of panaxynol on the reduction in high-molecular-weight adiponectin secretion from 3T3-L1 adipocytes treated with palmitic acids.
Takagi M, Kimura K, Nakashima KI, Inoue M.
Eur J Pharmacol. 2018 Feb 5;820:138-145. doi: 10.1016/j.ejphar.2017.12.028.

Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells.
Le HT, Nguyen HT, Min HY, Hyun SY, Kwon S, Lee Y, Le THV, Lee J, Park JH, Lee HY.
Cancer Lett. 2018 Jan 1;412:297-307. doi: 10.1016/j.canlet.2017.10.013.

Dietary polyacetylenes, falcarinol and falcarindiol, isolated from carrots prevents the formation of neoplastic lesions in the colon of azoxymethane-induced rats.
Kobaek-Larsen M, El-Houri RB, Christensen LP, Al-Najami I, Fretté X, Baatrup G.
Food Funct. 2017 Mar 22;8(3):964-974. doi: 10.1039/c7fo00110j.

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