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 | "Echinacea purpurea studies" by landingsafe (487 pt) | 2019-Nov-09 18:33 |
| Evaluation | N. Experts | Evaluation | N. Experts |
|---|---|---|---|
| 1 | 6 | ||
| 2 | 7 | ||
| 3 | 8 | ||
| 4 | 9 | ||
| 5 | 10 |
Echinacea purpurea extract has demonstrated good effects for the management of hyperglycemia and hypertension, thanks to phenols (27.04%), caffeic acid derivatives and ethanol, all components with antioxidant properties (1).
Effective against inflammation and chronic pain in osteoarthritis of the knee (2).
Most studies have not reported any significant reduction in cough symptoms. Only Cohen et al (3) found a significant improvement in nocturnal coughing. However, Echinacea decreased the symptoms of the common cold, reducing its duration (4).
This other study, which was also provided to support a commercial product, Echinaforce®, demonstrated the efficacy of Echinacea extract as an option for long-term preventive cold treatment (4 months) (5).
Pharmacodynamic studies have confirmed significant bronchodilator and anti-inflammatory effects of Echinacea, similar to the effects of classical synthetic drugs. Therefore, the results provide a scientific basis for the application of this herb in traditional medicine as an additional treatment for allergic respiratory disorders, such as asthma (6).
It is used as a supplement for athletes in order to increase performance. Echinacea was thought to improve oxygenation by increasing erythropoietin, a glycoprotein that regulates red blood cell formation. However, the published literature does not support the use of Echinacea as an ergogenic aid to improve aerobic capacity in untrained or healthy individuals (7).
Overall, even when ingested into Echinacea preparations up to 6 months at the recommended doses, no toxicological concern has emerged (8).
References___________________________________
(1) Antioxidant, Antidiabetic, and Antihypertensive Properties of Echinacea purpurea Flower Extract and Caffeic Acid Derivatives Using In Vitro Models.
Chiou SY, Sung JM, Huang PW, Lin SD.
J Med Food. 2017 Jan 6. doi: 10.1089/jmf.2016.3790
(2) The effect and safety of highly standardized Ginger (Zingiber officinale) and Echinacea (Echinacea angustifolia) extract supplementation on inflammation and chronic pain in NSAIDs poor responders. A pilot study in subjects with knee arthrosis.
Rondanelli M, Riva A, Morazzoni P, Allegrini P, Faliva MA, Naso M, Miccono A, Peroni G, Degli Agosti I, Perna S.
Nat Prod Res. 2016 Oct 13:1-5.
(3) Cohen HA, Varsano I, Kahan E, Sarrell EM, Uziel Y: Effectiveness of an herbal preparation containing Echinacea, propolis, and vitamin C in preventing respiratory tract infections in children: a randomized, double-blind, placebo-controlled, multicenter study. Arch Pediatr Adolesc Med 2004;158:217-221
(4) Herbal Medicine for Cough: a Systematic Review and Meta-Analysis.
Wagner L, Cramer H, Klose P, Lauche R, Gass F, Dobos G, Langhorst J.
Forsch Komplementmed. 2015;22(6):359-68. doi: 10.1159/000442111.
(5) Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold.
Ross SM.
Holist Nurs Pract. 2016 Jan-Feb;30(1):54-7. doi: 10.1097/HNP.0000000000000130.
(6) Echinacea complex--chemical view and anti-asthmatic profile.
Šutovská M, Capek P, Kazimierová I, Pappová L, Jošková M, Matulová M, Fraňová S, Pawlaczyk I, Gancarz R.
J Ethnopharmacol. 2015 Dec 4;175:163-71. doi: 10.1016/j.jep.2015.09.007
(7) Echinacea Supplementation: Does it Really Improve Aerobic Fitness?
Baumann CW, Kwak D.
J Exerc Nutrition Biochem. 2016 Sep;20(3):1-6.
Echinacea-Based Dietary Supplement Does Not Increase Maximal Aerobic Capacity in Endurance-Trained Men and Women.
Stevenson JL, Krishnan S, Inigo MM, Stamatikos AD, Gonzales JU, Cooper JA.
J Diet Suppl. 2016;13(3):324-38. doi: 10.3109/19390211.2015.1036189.
(8) Review and Assessment of Medicinal Safety Data of Orally Used Echinacea Preparations.
Ardjomand-Woelkart K, Bauer R.
Planta Med. 2016 Jan;82(1-2):17-31. doi: 10.1055/s-0035-1558096
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