Olaflur has demonstrated, compared to sodium fluoride, greater ability to counter the growth of Streptococcus mutans bacteria, lower amounts of bacterial protein and therefore appears to be superior to sodium fluoride for long-term use at low pH (1) .

Also with regard to dentinal hypersensitivity, in a toothpaste such as Elmex sensitive, Amine Fluoride has statistically demonstrated significant improvements compared to other toothpastes (2).

As far as caries is concerned, Amine Fluoride has provided excellent results with a decrease in lesion progression (3).

The results of this study support the current recommendation of using toothpastes with >1000 ppm F concentration in children with an increased caries risk in addition to spitting excess toothpaste with no rinsing following brushing (4).

The aim of this study was to investigate the effects of sodium fluoride (NaF) and amine fluoride (AmF) on bacterial viability in the oral cavity.
AmF has only little effect on the bacterial viability of oral biofilms. NaF application reduces the number of living bacteria in the oral biofilms. This effect lasts not longer than 120 min (5).

References_______________________________________________

(1) Barrak I, Urbán E, Turzó K, Nagy K, Braunitzer G, Stájer A. Short- and Long-Term Influence of Fluoride-Containing Prophylactics on the Growth of Streptococcus mutans on Titanium Surface. Implant Dent. 2015 Dec;24(6):675-9. doi: 10.1097/ID.0000000000000294. 

Brambilla E, Ionescu A, Cazzaniga G, Edefonti V, Gagliani M. The influence of antibacterial toothpastes on in vitro Streptococcus mutans biofilm formation: a continuous culture study. Am J Dent. 2014 Jun;27(3):160-6.

(2) Hamlin D, Mateo LR, Dibart S, Delgado E, Zhang YP, DeVizio W.   Comparative efficacy of two treatment regimens combining in-office and at-home programs for dentin hypersensitivity relief: a 24-week clinical study. -   Am J Dent. 2012 Jun

(3) Ekambaram M, Itthagarun A, King NM. Comparison of the remineralizing potential of child formula dentifrices. Int J Paediatr Dent. 2011 Mar;21(2):132-40. doi: 10.1111/j.1365-263X.2010.01101.x. 

(4) Nazzal H, Duggal MS, Kowash MB, Kang J, Toumba KJ. Comparison of residual salivary fluoride retention using amine fluoride toothpastes in caries-free and caries-prone children. Eur Arch Paediatr Dent. 2016 Jun;17(3):165-9. doi: 10.1007/s40368-015-0220-x.

(5) Naumova EA, Weber L, Pankratz V, Czenskowski V, Arnold WH. Bacterial viability in oral biofilm after tooth brushing with amine fluoride or sodium fluoride. Arch Oral Biol. 2019 Jan;97:91-96. doi: 10.1016/j.archoralbio.2018.10.013.