PVM/MA Copolymer (vinyl methyl ether-co-maleic anhydride) finds applications in nanocapsules as biocompatible and biodegradable and therefore useful for the preparation of drug delivery systems. It ha ...

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PVM/MA Copolymer (vinyl methyl ether-co-maleic anhydride) finds applications in nanocapsules as biocompatible and biodegradable and therefore useful for the preparation of drug delivery systems. It has a surfactant effect and has been tested in vitro in a formulation with Selol, intended for the treatment of pulmonary adenocarcinomas (1).

It has been shown to reduce tooth hypersensitivity, together with 8% arginine (2) both in dentifrices, and in mouthwashes (3).

References______________________________________________

(1) PVM/MA-shelled selol nanocapsules promote cell cycle arrest in A549 lung adenocarcinoma cells.
de Souza LR, Muehlmann LA, Dos Santos MS, Ganassin R, Simón-Vázquez R, Joanitti GA, Mosiniewicz-Szablewska E, Suchocki P, Morais PC, González-Fernández Á, Azevedo RB, Báo SN.  -  J Nanobiotechnology. 2014 Aug

(2) Efficacy in reducing dentine hypersensitivity of a regimen using a toothpaste containing 8% arginine and calcium carbonate, a mouthwash containing 0.8% arginine, pyrophosphate and PVM/MA copolymer and a toothbrush compared to potassium and negative control regimens: An eight-week randomized clinical trial

Augusto R. Elias Boneta, Karol Ramirez, Joselyn Naboa, Luis R. Mateo, Bernal Stewart, Foti Panagokos, William De Vizio  -  Journal of Dentistry March 1, 2013

(3) The development of a new desensitising mouthwash containing arginine, PVM/MA copolymer, pyrophosphates, and sodium fluoride—A hydraulic conductance study

Sarita V. MellocorrespondencePress enter key for correspondence informationemailPress enter key to Email the author, Evangelia Arvanitidou, Mark Vandeven  -  Journal of Dentistry March 1, 2013

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