Pea (Pisum sativum) is the well-known annual climbing plant that provides one of the most popular legumes that arrive on our table.

It belongs to the Fabaceae family and it's native to Asia.

The plant contains interesting substances useful for human health:

•     flavonoids
•     phenols
•     phytosterols
•     glycosides
•     saponins
•     tannins

It's a legume that has high protein, high fiber, low fat.

In a controlled diet, daily consumption of whole and fractionated yellow pea meal at doses equivalent to half a cup of yellow peas reduced insulin resistance in hypercholesterolaemic, while whole pea meal reduced android adiposity in women (1).

Purified peptides extracted from Pisum sativum have demonstrated a broad spectrum of antibacterial activity that can be used as a selective agent against infections and bacteria (2).

This study informs us that as the skin ages, impairment of extracellular matrix protein synthesis and increased action of degradative enzymes manifest as atrophy, wrinkles, and laxity. There is growing evidence for the functional role of exogenous peptides in many areas, including in offsetting the effects of skin aging. Here, using an artificial intelligence approach, RTE62G, a natural and unmodified peptide with extracellular matrix stimulatory properties, was identified. The predicted anti-aging properties of RTE62G peptide were then validated through in vitro, ex vivo, and proof-of-concept clinical trials (3).

Pisum sativum studies

References_________________________________________________________________

(1) Marinangeli CP, Jones PJ. Br J Whole and fractionated yellow pea flours reduce fasting insulin and insulin resistance in hypercholesterolaemic and overweight human subjects.  Nutr. 2011 Jan;105(1):110-7. doi: 10.1017/S0007114510003156

(2) S Rehman, A Khanum - Pak. J. Isolation and characterization of peptide (s) from Pisum sativum having antimicrobial activity against various bacteria   Bot., 43(6): 2971-2978, 2011.

(3) Kennedy K, Cal R, Casey R, Lopez C, Adelfio A, Molloy B, Wall AM, Holton TA, Khaldi N. The anti-ageing effects of a natural peptide discovered by artificial intelligence. Int J Cosmet Sci. 2020 Aug;42(4):388-398. doi: 10.1111/ics.12635.