Guaiazulene has been shown to be effective, with local application, in the treatment of diaper rash in high-risk infants (1). Laboratory studies have confirmed the antioxidant activity of Guaiazulene ...

Read the full Tiiip

(Send your comment)

Guaiazulene has been shown to be effective, with local application, in the treatment of diaper rash in high-risk infants (1).

Laboratory studies have confirmed the antioxidant activity of Guaiazulene (2) which is used as an agent against gastric ulcer (3) and plays a hepatoprotective function (4).

References__________________________________

(1) Guaiazulene: a new treatment option for recalcitrant diaper dermatitis in NICU patients.
Gunes T, Akin MA, Sarici D, Hallac K, Kurtoglu S, Hashimoto T.
J Matern Fetal Neonatal Med. 2013 Jan
(2) Antioxidant activity of guaiazulene and protection against paracetamol hepatotoxicity in rats.
Kourounakis AP, Rekka EA, Kourounakis PN.
J Pharm Pharmacol. 1997 Sep
(3) Synthesis and Biological Evaluation of 3, 8-dimethyl-5-isopropylazulene Derivatives as Anti-gastric Ulcer Agent.
Cao T, Li Y, Yang Z, Yuan M, Li Y, Yang H, Feng Y, Yin S.
Chem Biol Drug Des. 2016 Aug
(4) Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach.
Vinholes J, Rudnitskaya A, Gonçalves P, Martel F, Coimbra MA, Rocha SM.
Food Chem. 2014 May

Sign up to vote this object, vote his reviews and to contribute to Tiiips.Evaluate