Palmitoyl tetrapeptide-7 is a peptide used in cosmetics for its anti-aging action, increasing elasticity and skin tone.
The name describes the structure of the molecule:
- Palmitoyl - This indicates that the molecule has a palmitic acid moiety attached to it. Palmitic acid is a saturated fatty acid with the formula CH₃(CH₂)₁₄COOH. The "palmitoyl" part refers to the fatty acid chain without the terminal hydroxyl group, which is CH₃(CH₂)₁₄CO-.
- Tetrapeptide - This indicates that the molecule contains a peptide chain made up of four amino acids. "Tetra" means four, and "peptide" refers to a chain of amino acids linked by peptide bonds.
- -7 - This number typically refers to a specific sequence or variant of a tetrapeptide. It doesn't provide direct information about the structure, but it distinguishes this particular tetrapeptide from others.
Description of raw materials used in production:
- Amino acids - The specific amino acids used to synthesize palmitoyl tetrapeptide-7 can vary, but they typically include glycine, glutamic acid, alanine, and lysine. These amino acids serve as the building blocks for the peptide chain.
- Palmitic acid - Palmitic acid, a saturated fatty acid, is used to introduce the palmitoyl group into the peptide structure. It is commonly derived from natural sources such as palm oil or coconut oil.
Summary of the industrial synthesis process step-by-step:
- Preparation of amino acids - The required amino acids (glycine, glutamic acid, alanine, and lysine) are prepared or acquired as individual components.
- Activation of amino acids - Each amino acid is activated by attaching a protective group to its reactive functional group, ensuring controlled and selective peptide bond formation during the subsequent coupling reactions.
- Coupling reactions - The activated amino acids are combined in a specific order and undergo a series of coupling reactions. This results in the formation of the desired tetrapeptide chain.
- Deprotection - The protective groups attached to the amino acids are removed to expose the reactive functional groups required for further modifications.
- Attachment of palmitic acid - Palmitic acid is introduced by coupling it with the amino acid sequence. This step involves activation of the carboxyl group of palmitic acid and its reaction with the amino group of the terminal amino acid in the peptide chain.
- Purification - The crude product is purified using techniques such as chromatography or filtration to remove any impurities or unreacted starting materials.
- Characterization - The synthesized palmitoyl tetrapeptide-7 is characterized through various analytical methods to confirm its structure, purity, and quality.
- Formulation - Palmitoyl tetrapeptide-7 is incorporated into skincare and cosmetic formulations at appropriate concentrations to utilize its anti-aging and skin-restorative properties.
- Packaging and distribution - The final product is packaged and distributed for use in various skincare and cosmetic products.
What it is for and where
Cosmetics
Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
"Palmitoyl tetrapeptide-7 studies"
- Molecular Formula: C34H62N8O7
- Molecular Weight: 694.919 g/mol
- CAS: 221227-05-0
- UNII: Q41S464P1R
Synonyms:
- Pal-Gly-Gln-Pro-Arg-OH
- N-Palmitoylrigin
- N-Palmitoyl-Gly-L-Gln-L-Pro-L-Arg-OH
- Palmitoyl-GQPR
- l-Arginine, N-(1-oxohexadecyl)glycyl-l-glutaminyl-l-prolyl-
- palmitoylglycyl-L-glutaminyl-L-prolyl-L-arginine
