L-acetylcarnitine is an acetyl ester of L-carnitine, which is synthesized through acetyltransferase from the amino acid Carnitine and transported into the brain through an active transport operationally expressed in the blood/brain barrier.

Take only under medical supervision

What it is used for and where

As with any supplement, it is advisable to consult a doctor before taking L-acetylcarnitine.

Medical

L-acetylcarnitine modulates the activity of the nerve growth factor and modulates various neurotransmitter systems including the cholinergic and dopaminergic system (1).

It is used as a drug for the treatment of neuropathic pain of various origins.

It is credited with specific health benefits:

Peripheral neuropathy: peripheral neuropathy refers to damage or dysfunction of peripheral nerves, often causing numbness, pain or tingling in the extremities. L-acetyl carnitine has been studied for its potential role in the management of peripheral neuropathy, particularly in individuals with diabetes.

Neuroprotection: L-acetyl carnitine has been studied for its neuroprotective properties. It may help protect against age-related cognitive decline and certain neurodegenerative diseases.

Physical performance: L-acetyl carnitine has been studied for its potential benefits in improving athletic performance. It may improve exercise tolerance, reduce muscle fatigue and support muscle recovery.

Like all drugs it can cause side effects. Always ask the physician.

The most relevant studies on this chemical compound have been selected with a summary of their contents:

L-acetylcarnitine studies

• Molecular Formula: C₉H₁₇NO₄
• Molecular Weight: 203.238 g/mol
• CAS: 3040-38-8
• EC Number: 608-476-7
• UNII: 6DH1W9VH8Q
• FEMA Number:

• Acetyl-L-carnitine
• O-Acetyl-L-carnitine
• L-Carnitine acetyl ester
• L-ACETYLCARNITINE
• Acetyl-L-(-)-carnitine
• Levocarnitine acetyl
• O-acetylcarnitine
• L-O-Acetylcarnitine
• (3R)-3-acetyloxy-4-(trimethylazaniumyl)butanoate
• (R)-Acetylcarnitine
• Acetylcarnitine, L-
• (-)-Acetylcarnitine
• 1-Propanaminium, 2-(acetyloxy)-3-carboxy-N,N,N-trimethyl-, hydroxide, inner salt, (R)-
• R-Acetylcarnitine
• Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, acetate, L-
• Nicetile
• acetylcarnitine

References_______________________________________________________________________

(1) Imperato A, Ramacci MT, Angelucci L. Acetyl-Lcarnitine enhances acetylcholine release in the striatum and hippocampus of awake freely moving rats. Neurosci. Lett. 1989;107:251–5