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Propylene carbonate
"Description"
by AColumn (9309 pt)
2019-May-25 12:43

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What is Propylene carbonate

It is a biodegradable aliphatic polycarbonate derived from carbon dioxide and propylene oxide. It has a rather low glass transition temperature and becomes brittle at low temperature.

What is it for?

It is effective as a cleaner on hard surfaces, resins, glass fibers and polyurethanes.
It can be used as an intermediate reagent in the formation of carbamate, transesterification.

Most significant studies

An alternative low toxicity solvent (propylene carbonate; PC) proposed for the preparation of poly(lactic-co-glycolic-acid) microparticles (1).

Block polymer for drug delivery (2).

Molecular Formula :  C4H6O3

Molecular Weight : 102.089 g/mol

CAS : 108-32-7

Synonyms :

  • Carbonic acid, cyclic propylene ether
  • 4-Methyl-2-oxo-1,3-dioxolane
  • 1,3-Dioxolan-2-one, 4-methyl-
  • Cyclic propylene carbonate
  • 4-Methyl-1,3-dioxolan-2-one
  • 1,2-Propylene carbonate
  • 1,2-Propanediol cyclic carbonate
  • 1-Methylethylene carbonate
  • Cyclic 1,2-propylene carbonate
  • Dipropylene carbonate
  • EINECS 203-572-1

References__________________

(1) Microparticle preparation by a propylene carbonate emulsification-extraction method.

Grizić D, Lamprecht A.

Int J Pharm. 2018 Jun 10;544(1):213-221. doi: 10.1016/j.ijpharm.2018.03.062. Epub 2018 Apr 6.

(2) Synthesis and characterization of amphiphilic block polymer poly(ethylene glycol)-poly(propylene carbonate)-poly(ethylene glycol) for drug delivery.

Li H, Niu Y.

Mater Sci Eng C Mater Biol Appl. 2018 Aug 1;89:160-165. doi: 10.1016/j.msec.2018.04.002. Epub 2018 Apr 5.

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