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Isovitexin
"Descrizione"
by AColumn (9309 pt)
2019-Oct-30 18:28

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What is Isovitexin

Isovitexin (apigenin-6-C-glucoside) is an active component found in various medicinal plants and is an isomer of vitexin (apigenin-6-C-glucoside).

Where is it ?

Some plants that contain it:

  • Ficus deltoidea (1)
  • Microcos paniculata L. (2)
  • Jatropha curcas (3)
  • and several others.
It is considered an antioxidant, anti-tumor, anti-inflammatory, neuroprotective (4).
 
Molecular formula: C21H20O10

Molecular weight: 432.38

CAS: 222-963-8

Synonyms:

  • Apigenin-6-C-glucoside
  • 6-Glucosylapigenin
  • 6-C-Glucosylapigenin
  • Apigenin 6-C-glucoside
  • (1S)-1,5-anhydro-1-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol
  • 4H-1-Benzopyran-4-one, 6-beta-D-glucopyranosyl-5,7-dihydroxy-2-
    (4-hydroxyphenyl)-
  • beta-D-isovitexin
  • Apigenin 6-C-beta-glucopyranoside

References___________________________

(1) Mistletoe fig (Ficus deltoidea Jack) leaf extract prevented postmenopausal osteoarthritis by attenuating inflammation and cartilage degradation in rat model.

Che Ahmad Tantowi NA, Hussin P, Lau SF, Mohamed S.

Menopause. 2017 Jun 19. doi: 10.1097/GME.0000000000000882

(2) Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice.

Wu H, Zhang G, Huang L, Pang H, Zhang N, Chen Y, Wang G.

Oxid Med Cell Longev. 2017;2017:3631565. doi: 10.1155/2017/3631565. 

(3) Assessment of Antioxidant and Cytoprotective Potential of Jatropha (Jatropha curcas) Grown in Southern Italy.

Papalia T, Barreca D, Panuccio MR.

Int J Mol Sci. 2017 Mar 18;18(3). pii: E660. doi: 10.3390/ijms18030660.

(5) A review on the pharmacological effects of vitexin and isovitexin.

He M, Min JW, Kong WL, He XH, Li JX, Peng BW.

Fitoterapia. 2016 Dec;115:74-85. doi: 10.1016/j.fitote.2016.09.011. 

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