"Descrizione" by A_Partyns (12876 pt) | 2022-Nov-22 09:52 |
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Dicalcium phosphate or Brushite is obtained from the sedimentary phosphate rock enriched with natural radionuclide concentrations (1).
D stands for Dihydratate and is composed of calcium oxide and phosphoric acid-
Density 2.854 g/ml
Most significant studies
Calcium phosphate cements (CPCs) are synthetic bone grafting materials that can be used in fracture stabilization and to fill bone voids after, e.g., bone tumour excision. Currently there are several calcium phosphate-based formulations available, but their use is partly limited by a lack of knowledge of their mechanical properties, in particular their resistance to mechanical loading over longer periods of time. Furthermore, depending on, e.g., setting conditions, the end product of acidic CPCs may be mainly brushite or monetite, which have been found to behave differently under quasi-static loading. The objectives of this study were to evaluate the compressive fatigue properties of acidic CPCs, as well as the effect of phase composition on these properties. Hence, brushite cements stored for different lengths of time and with different amounts of monetite were investigated under quasi-static and dynamic compression. Both storage and brushite-to-monetite phase transformation was found to have a pronounced effect both on quasi-static compressive strength and fatigue performance of the cements, whereby a substantial phase transformation gave rise to a lower mechanical resistance. The brushite cements investigated in this study had the potential to survive 5 million cycles at a maximum compressive stress of 13 MPa. Given the limited amount of published data on fatigue properties of CPCs, this study provides an important insight into the compressive fatigue behaviour of such materials (2).
In this work, the macroporous cements of Brushite have been fabricated by foaming cement paste, using two different synthetic surfactants and show potential for future clinical use, both as fillers of bone voids and as scaffolds for bone regeneration in vitro (3).
Molecular Formula : CaHO4P or CaHPO4 or CaHPO4
Molecular Weight : 136.056 g/mol
CAS : 7757-93-9
References______________________
(1) Dose assessment to workers in a dicalcium phosphate production plant.
Mulas D, Garcia-Orellana J, Casacuberta N, Hierro A, Moreno V, Masqué P.
J Environ Radioact. 2016 Dec;165:182-190. doi: 10.1016/j.jenvrad.2016.09.018. Epub 2016 Oct 8.
(2) Compressive fatigue properties of an acidic calcium phosphate cement-effect of phase composition.
Ajaxon I, Öhman Mägi C, Persson C.
J Mater Sci Mater Med. 2017 Mar;28(3):41. doi: 10.1007/s10856-017-5851-5. Epub 2017 Jan 31.
(3) Brushite foams--the effect of Tween® 80 and Pluronic® F-127 on foam porosity and mechanical properties.
Unosson J, Montufar EB, Engqvist H, Ginebra MP, Persson C.
J Biomed Mater Res B Appl Biomater. 2016 Jan;104(1):67-77. doi: 10.1002/jbm.b.33355. Epub 2015 Jan 23.
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