White horehound (Marrubium vulgare L.) is a perennial, aromatic herb belonging to the Lamiaceae family and blooms with white oblong flowers.It is found in Europe, North Africa, Asia.Inside there is th ...

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White horehound (Marrubium vulgare L.) is a perennial, aromatic herb belonging to the Lamiaceae family and blooms with white oblong flowers.
It is found in Europe, North Africa, Asia.

Inside there is the Marrubiin, a component that gives the bitter taste to the Marrubium and that has antioxidant properties.

In this study, the results show that a methanolic extract of Marrubiin protects the myocardium against acute myocardial infarction induced by isoproterenol and suggests that the effects may be related to antioxidant activity (1).

Methanol extract and Marrubin diterpene obtained from Marrubian leaves have demonstrated gastroprotective properties this effect can be partly attributed to isolated diterpene (2).

In Algeria, this plant is traditionally used against diabetes and, within it have been identified flavonoids, chlorogenic acid (3).

It also exerts an analgesic action, related to the presence of steroids and terpenes detected by TLC analysis (4) and an antispasmodic activity (5).

White horehound studies

References___________________________________________

(1) Yousefi K, Soraya H, Fathiazad F, Khorrami A, Hamedeyazdan S, Maleki-Dizaji N. et al. Cardioprotective effect of methanolic extract of Marrubium vulgare L. On isoproterenol-induced acute myocardial infarction in rats. Indian J Exp Biol. 2013;51(8):653–60

(2) de Oliveira AP, Santin JR, Lemos M, Klein Júnior LC, Couto AG, da Silva Bittencourt CM. et al. Gastroprotective activity of methanol extract and marrubiin obtained from leaves of Marrubium vulgare L. (Lamiaceae) J Pharm Pharmacol. 2011;63(9):1230–7. doi: 10.1111/j.2042-7158.2011.01321.x

(3) Boudjelal A, Henchiri C, Siracusa L, Sari M, Ruberto G. Compositional analysis and in vivo anti-diabetic activity of wild Algerian Marrubium vulgare L. infusion. Fitoterapia. 2012;83(2):286–92. doi: 10.1016/j.fitote.2011.11.005

(4) de Souza MM, de Jesus RA, Cechinel-Filho V, Schlemper V. Analgesic profile of hydroalcoholic extract obtained from Marrubium vulgare. Phytomedicine. 1998;5(2):103–7. doi: 10.1016/S0944-7113(98)80005-6

(5) Schlemper V, Ribas A, Nicolau M, Cechinel Filho V. Antispasmodic effects of hydroalcoholic extract of Marrubium vulgare on isolated tissues. Phytomedicine. 1996;3(2):211–6. doi: 10.1016/S0944-7113(96)80038-9

 

 

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