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 | "Citral, studies" by Ottika11 (2065 pt) | 2019-Oct-17 18:59 |
| Evaluation | N. Experts | Evaluation | N. Experts |
|---|---|---|---|
| 1 | 6 | ||
| 2 | 7 | ||
| 3 | 8 | ||
| 4 | 9 | ||
| 5 | 10 |
Citral is a chemical component found in citrus, fruit and vegetables. In particular it is found in citronella where it is the main component with about 68.78%. It has demonstrated protection against induced oxidative stress and could be a promising agent for lung cancer chemoprevention (1).
Stable and safe for the skin (2), Citral has proved to be an excellent bactericide for use in the treatment of drug-resistant infections (3).
Citral exhibited a strong cytotoxic effect and anti-inflammatory activity in a RAW 264.7 cell line (4).
Citral could be a lead candidate phytomolecule for further developing it into an anti-staphylococcal agent (5).
References__________________
(1) Protective effects of lemongrass essential oil against benzo(a)pyrene induced oxidative stress and DNA damage in human embryonic lung fibroblast cells.
Jiang J, Xu H, Wang H, Zhang Y, Ya P, Yang C, Li F.
Toxicol Mech Methods. 2016 Nov
(2) Effects of Carbopol® 934 proportion on nanoemulsion gel for topical and transdermal drug delivery: a skin permeation study.
Zheng Y, Ouyang WQ, Wei YP, Syed SF, Hao CS, Wang BZ, Shang YH.
Int J Nanomedicine. 2016 Nov
(3) Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral.
Adukwu EC, Bowles M, Edwards-Jones V, Bone H.
Appl Microbiol Biotechnol. 2016 Nov
(4) Anti-inflammatory and anti-cancer activity of citral: Optimization of citral-loaded solid lipid nanoparticles (SLN) using experimental factorial design and LUMiSizer®.
Zielińska A, Martins-Gomes C, Ferreira NR, Silva AM, Nowak I, Souto EB.
Int J Pharm. 2018 Dec 20;553(1-2):428-440. doi: 10.1016/j.ijpharm.2018.10.065.
(5) Citral, a monoterpenoid aldehyde interacts synergistically with norfloxacin against methicillin resistant Staphylococcus aureus.
Gupta P, Patel DK, Gupta VK, Pal A, Tandon S, Darokar MP.
Phytomedicine. 2017 Oct 15;34:85-96. doi: 10.1016/j.phymed.2017.08.016.
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