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 | "Pregelatinised starch, studies" by CarPas (5225 pt) | 2019-Mar-17 09:40 |
| Evaluation | N. Experts | Evaluation | N. Experts |
|---|---|---|---|
| 1 | 6 | ||
| 2 | 7 | ||
| 3 | 8 | ||
| 4 | 9 | ||
| 5 | 10 |
The use of pregelatinised starch as an excipient in the production of hard capsules could be useful in terms of reducing the coefficient of variability of the filling weight (1).
The physical and mechanical properties of a Amprac 01 acetate pregelatinized starch were studied, obtained with the solvent jet method, a way to study the film formation capacity of this modified starch and the effects when several plasticizers are added (2)
This study evaluated the value of the tensile strength of pregelatinised starch that appeared to be similar to that of microcrystalline cellulose (3).
References___________________________
(1) Investigations into the use of pregelatinised starch to develop powder-filled hard capsules.
Gohil UC, Podczeck F, Turnbull N.
Int J Pharm. 2004 Nov 5;285(1-2):51-63.
(2) Effect of plasticizers on properties of pregelatinised starch acetate (Amprac 01) free films.
Bonacucina G, Di Martino P, Piombetti M, Colombo A, Roversi F, Palmieri GF.
Int J Pharm. 2006 Apr 26;313(1-2):72-7. Epub 2006 Feb 28
(3) The strength of bilayered tablets.
Podczeck F, Drake KR, Newton JM, Haririan I.
Eur J Pharm Sci. 2006 Dec;29(5):361-6. Epub 2006 Jul 25.
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