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 | "Petrolatum studies" by Street82 (2968 pt) | 2020-Dec-02 18:16 |
| Evaluation | N. Experts | Evaluation | N. Experts |
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| 1 | 6 | ||
| 2 | 7 | ||
| 3 | 8 | ||
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| 5 | 10 |
Glyceryl monooleate was a potassium penetrant enhancer for petrolatum in this in vitro analysis (1).
Effect of petrolatum coating on fast-absorbing gut suture (2).
The rheological properties of petrolatum which depend on both temperature and thermal history are studied. It has been shown that the rheological differences in petrolatum can be explained by the number of lamellar cells present, so that there are more lamellar piles, the more the petrolatum is rigid (3).
Safety
This study reports the case of a young woman who contracted exogenous lipoid pneumonia due to the chronic use of petrolatum-based Vicks VapoRub nasal ointment. A rather rare case (4).
References___________________________________
(1) In vitro skin penetration of petrolatum and soybean oil and effects of glyceryl monooleate.
Intarakumhaeng R, Shi Z, Wanasathop A, Stella QC, Wei KS, Styczynski PB, Li C, Smith ED, Li SK.
Int J Cosmet Sci. 2018 Aug;40(4):367-376. doi: 10.1111/ics.12469. Epub 2018 Aug 15.
(2) Effect of petrolatum coating on fast-absorbing gut suture.
Susong JR, Neiner JR.
J Am Acad Dermatol. 2018 Nov;79(5):952-953. doi: 10.1016/j.jaad.2018.04.041. Epub 2018 Apr 30.
(3) Study of petrolatum structure: Explaining its variable rheological behavior.
van Heugten AJP, Landman J, Petukhov AV, Vromans H.
Int J Pharm. 2018 Apr 5;540(1-2):178-184. doi: 10.1016/j.ijpharm.2018.02.016. Epub 2018 Feb 13.
(4) Nasal application of petrolatum ointment - A silent cause of exogenous lipoid pneumonia: Successfully treated with prednisolone.
Kilaru H, Prasad S, Radha S, Nallagonda R, Kilaru SC, Nandury EC.
Respir Med Case Rep. 2017 Jul 8;22:98-100. doi: 10.1016/j.rmcr.2017.07.003. eCollection 2017.
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