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 | "Urea studies" by FRanier (9976 pt) | 2019-Mar-21 05:45 |
| Evaluation | N. Experts | Evaluation | N. Experts |
|---|---|---|---|
| 1 | 6 | ||
| 2 | 7 | ||
| 3 | 8 | ||
| 4 | 9 | ||
| 5 | 10 |
In this study, urea was effective in correcting chronic hyponatremia among cancer patients with Syndrome of inappropriate antidiuresis (2).
The problem of detoxification of urban solid waste has been addressed with an effective treatment technology. It is possible to eliminate dioxin in municipal solid waste incinerator ashes with the addition of urea, which represents a promising alternative to current methods (3).
The known characteristics of the Herpes simplex virus type 1 (HSV1) are, in general, lifelong latency and symptoms both during the first infection and after reactivation. The aim of the present study was to describe a protocol to generate a reliable and discriminative avidity index for anti-HSV1 IgG content in human sera (4).
Urea is safe and effective in fluid restriction-refractory hyponatraemia (5).
To effectively reduce formaldehyde levels in the dissection room and thus ensure the safety of students and educators, urea in the form of a spray comes from the authors of this study, considered an effective solution (6).
The role of urea in the concentration of urine is quite known, but the sodium balance on urea manipulation via urea transporters (UTs), UT-A1 and UT-A3 is described in this study (7).
References__________________________________
(1) RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals.
Lesch M, Luckner M, Meyer M, Weege F, Gravenstein I, Raftery M, Sieben C, Martin-Sancho L, Imai-Matsushima A, Welke RW, Frise R, Barclay W, Schönrich G, Herrmann A, Meyer TF, Karlas A.
PLoS Pathog. 2019 Mar 18;15(3):e1007601. doi: 10.1371/journal.ppat.1007601. eCollection 2019 Mar.
(2) Urea in cancer patients with chronic SIAD-induced hyponatremia: old drug, new evidence.
Nervo A, D'Angelo V, Rosso D, Castellana E, Cattel F, Arvat E, Grossi E.
Clin Endocrinol (Oxf). 2019 Mar 13. doi: 10.1111/cen.13966
(3) Detoxification of municipal solid waste incinerator (MSWI) fly ash by single-mode microwave (MW) irradiation: Addition of urea on the degradation of Dioxin and mechanism.
Deng D, Qiao J, Liu M, Kolodynska D, Zhang M, Dionysiou DD, Ju Y, Ma J, Chang MB.
J Hazard Mater. 2019 May 5;369:279-289. doi: 10.1016/j.jhazmat.2019.01.001. Epub 2019 Feb 3.
(4) Urea dilution of serum for reproducible anti-HSV1 IgG avidity index.
Olsson J, Johansson J, Honkala E, Blomqvist B, Kok E, Weidung B, Lövheim H, Elgh F.
BMC Infect Dis. 2019 Feb 14;19(1):164. doi: 10.1186/s12879-019-3769-x.
(5) Urea treatment in fluid restriction-refractory hyponatraemia.
Lockett J, Berkman KE, Dimeski G, Russell AW, Inder WJ.
Clin Endocrinol (Oxf). 2019 Apr;90(4):630-636. doi: 10.1111/cen.13930. Epub 2019 Jan 25.
(6) Spraying urea solution reduces formaldehyde levels during gross anatomy courses.
Kawata S, Marutani E, Hirai S, Hatayama N, Omotehara T, Nagahori K, Li Z, Miyaso H, Pieroh P, Naito M, Itoh M.
Anat Sci Int. 2019 Mar;94(2):209-215. doi: 10.1007/s12565-018-00474-y. Epub 2019 Jan 2.
(7) Lack of urea transporters, UT-A1 and UT-A3, increases nitric oxide accumulation to dampen medullary sodium reabsorption through ENaC.
Rogers RT, Sun MA, Yue Q, Bao HF, Sands JM, Blount MA, Eaton DC.
Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F539-F549. doi: 10.1152/ajprenal.00166.2018. Epub 2018 Dec 12
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