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 | "Descrizione" by A_Partyns (12876 pt) | 2020-Feb-07 09:44 |
Arachidic acid is a Very-long-chain (20:0) polyunsaturated fatty acid found in nature in small amounts in peanuts
The intake of arachidic acid showed, in 184 subjects, a lower risk factor regarding pregnancy-induced hypertension, compared to other fatty acids such as myristic acid and palmitic acid (1).
An inverse relationship has also been observed between arachidic acid and cardiometabolic conditions with a lower risk of type 2 diabetes mellitus (2).
Other studies
Circulating Very Long-Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study.
Lemaitre RN, McKnight B, Sotoodehnia N, Fretts AM, Qureshi WT, Song X, King IB, Sitlani CM, Siscovick DS, Psaty BM, Mozaffarian D.
J Am Heart Assoc. 2018 Nov 6;7(21):e010019. doi: 10.1161/JAHA.118.010019.
Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer's Disease (AD) Pathology Than in Severe AD Pathology.
Nasaruddin ML, Pan X, McGuinness B, Passmore P, Kehoe PG, Hölscher C, Graham SF, Green BD.
Metabolites. 2018 Oct 26;8(4). pii: E69. doi: 10.3390/metabo8040069
Fabrication of self-assembled vesicle nanoparticles of poly(l-lysine)-arachidic acid conjugates for a vascular endothelial growth factor carrier.
Chen PC, Prasannan A, Huang CC, Tang SF, Tsai HC.
Mater Sci Eng C Mater Biol Appl. 2017 Sep 1;78:756-762. doi: 10.1016/j.msec.2017.04.092
Molecular Formula: C20H40O2
Molecular Weight: 312.5 g/mol
CAS: 506-30-9
EC Number: 208-031-3
DSSTox Substance ID: DTXSID1060134
NSC number 93983
References___________________________________________
(1) Association of circulating saturated fatty acids with the risk of pregnancy-induced hypertension: a nested case-control study. Li X, Huang Y, Zhang W, Yang C, Su W, Wu Y, Chen X, Zhou A, Huo X, Xia W, Xu S, Chen D, Li Y. Hypertens Res. 2020 Jan 9. doi: 10.1038/s41440-019-0383-7
(2) Circulating Very-Long-Chain SFA Concentrations Are Inversely Associated with Incident Type 2 Diabetes in US Men and Women. Ardisson Korat AV, Malik VS, Furtado JD, Sacks F, Rosner B, Rexrode KM, Willett WC, Mozaffarian D, Hu FB, Sun Q. J Nutr. 2019 Oct 16. pii: nxz240. doi: 10.1093/jn/nxz240
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