The most significant and most recent studies concerning L-Lysine applications:
Identification of ε-Poly-L-lysine as an Antimicrobial Product from an Epichloë Endophyte and Isolation of Fungal ε-PL Synthetase Gene.
Purev E, Kondo T, Takemoto D, Niones JT, Ojika M.
Molecules. 2020 Feb 25;25(5). pii: E1032. doi: 10.3390/molecules25051032.
Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new l-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIα inhibitors.
Pedatella S, Cerchia C, Manfra M, Cioce A, Bolognese A, Lavecchia A.
Eur J Med Chem. 2020 Feb 1;187:111960. doi: 10.1016/j.ejmech.2019.111960.
Deregulation of the Histone Lysine-Specific Demethylase 1 Is Involved in Human Hepatocellular Carcinoma.
Kim S, Bolatkan A, Kaneko S, Ikawa N, Asada K, Komatsu M, Hayami S, Ojima H, Abe N, Yamaue H, Hamamoto R.
Biomolecules. 2019 Dec 1;9(12). pii: E810. doi: 10.3390/biom9120810.
Sonochemical preparation of folic acid-decorated reductive-responsive ε-poly-L-lysine-based microcapsules for targeted drug delivery and reductive-triggered release.
Shi C, Zhong S, Sun Y, Xu L, He S, Dou Y, Zhao S, Gao Y, Cui X.
Mater Sci Eng C Mater Biol Appl. 2020 Jan;106:110251. doi: 10.1016/j.msec.2019.110251.
L-Lysine as the Molecule Influencing Selective Brain Activity in Pain-Induced Behavior of Rats.
Severyanova LA, Lazarenko VA, Plotnikov DV, Dolgintsev ME, Kriukov AA.
Int J Mol Sci. 2019 Apr 17;20(8). pii: E1899. doi: 10.3390/ijms20081899.
Drug properties of fosravuconazole L-lysine ethanolate (NAILIN® Capsules 100 mg), a new oral azole therapeutic for onychomycosis: an analysis based on non-clinical and clinical trial data.
Nakano M, Aoki Y, Yamaguchi H.
Nihon Yakurigaku Zasshi. 2019;153(2):79-87. doi: 10.1254/fpj.153.79.
Influence of poly-l-lysine molecular weight on antibacterial efficacy in polymer multilayer films.
Alkekhia D, Shukla A.
J Biomed Mater Res A. 2019 Jun;107(6):1324-1339. doi: 10.1002/jbm.a.36645
Nano-complexation of ε-poly-l-lysine with DNA: Improvement of antimicrobial activity under high phosphate conditions.
Jiang S, Zeng M, Zhao Y, Wu H, Zhang F.
Int J Biol Macromol. 2019 Apr 15;127:349-356. doi: 10.1016/j.ijbiomac.2018.12.110.
Biocompatible antimicrobial electrospun nanofibers functionalized with ε-poly-l-lysine.
Amariei G, Kokol V, Vivod V, Boltes K, Letón P, Rosal R.
Int J Pharm. 2018 Dec 20;553(1-2):141-148. doi: 10.1016/j.ijpharm.2018.10.037.
Dietary L-lysine supplementation altered the content of pancreatic polypeptide, enzymes involved in glutamine metabolism, and β-actin in rats.
Xiao CW, Faddoul C, Wood C.
Amino Acids. 2018 Dec;50(12):1729-1737. doi: 10.1007/s00726-018-2648-x.
Effects of ε-Poly-l-lysine on the cell wall of Saccharomyces cerevisiae and its involved antimicrobial mechanism.
Tan Z, Bo T, Guo F, Cui J, Jia S.
Int J Biol Macromol. 2018 Oct 15;118(Pt B):2230-2236. doi: 10.1016/j.ijbiomac.2018.07.094.
L-Lysine Attenuates Hepatic Steatosis in Senescence-Accelerated Mouse Prone 8 Mice.
Sato T, Muramatsu N, Ito Y, Yamamoto Y, Nagasawa T.
J Nutr Sci Vitaminol (Tokyo). 2018;64(3):192-199. doi: 10.3177/jnsv.64.192.
Plasma L-Carnitine and L-Lysine Concentrations in HIV-Infected Patients.
Butorov EV.
Open Biochem J. 2017 Dec 28;11:119-131. doi: 10.2174/1874091X01711010119.
d,l-lysine functionalized Fe3O4 nanoparticles for detection of cancer cells.
Antal I, Koneracka M, Kubovcikova M, Zavisova V, Khmara I, Lucanska D, Jelenska L, Vidlickova I, Zatovicova M, Pastorekova S, Bugarova N, Micusik M, Omastova M, Kopcansky P.
Colloids Surf B Biointerfaces. 2018 Mar 1;163:236-245. doi: 10.1016/j.colsurfb.2017.12.022.
