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 | "Descrizione" by AColumn (9309 pt) | 2020-Apr-13 12:37 |
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Bromelain is a biomolecule, a proteolytic enzyme that is extracted from the fruit and stem of the pineapple (Ananas comosus), but is also present in the skin and leaves.
It's composed of ananaine, comosaine, cystatin, calcium, carbohydrates.
It is used as an anti-inflammatory, to relieve pain caused by arthritis, wound healing with reduced side effects when compared to non-steroidal anti-inflammatory drugs
Bromelain has a direct impact on cancer cells and their microenvironment and also acts on the modulation of the immune, inflammatory and haemostatic systems (1).
Bromelain based on selective enzymes is also an effective treatment modality for delayed presentation burns and chronic wounds (2).
From this preliminary study it can be deduced that the use of the gastro-resistant formulation containing the mixture of Boswellia and bromelain supplements can be a valuable non-pharmacological tool to improve the quality of life of patients suffering from different forms of osteoarthritis (3).
Scientific insights on Bromelain
Enzyme Commission (EC) Number 3.4.22.32 formerly EC 3.4.22.4
EC Number 253-387-5
CAS Number 37189-34-7
MDL number MFCD00081423
NACRES NA.54
References_________________________________________________________________________
(1) Chobotova K, Vernallis AB, Majid FA. Bromelain's activity and potential as an anti-cancer agent: Current evidence and perspectives. Cancer Lett. 2010;290(2):148–156. doi:10.1016/j.canlet.2009.08.001
(2) Harats M, Haik J, Cleary M, Vashurin I, Aviv U, Kornhaber R. A Retrospective Review of an Off-label Bromelain-based Selective Enzymatic Debridement (Nexobrid®) in the Treatment of Deep, Partial, and Full Thickness Burns and Hard to Heal Wounds. Isr Med Assoc J. 2020;22(2):83–88.
(3) Italiano G, Raimondo M, Giannetti G, Gargiulo A. Benefits of a Food Supplement Containing Boswellia serrata and Bromelain for Improving the Quality of Life in Patients with Osteoarthritis: A Pilot Study. J Altern Complement Med. 2020;26(2):123–129. doi:10.1089/acm.2019.0258
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