The in-depth studies on Hederagenin cover the latest studies on its applications and its availability.
Del Hierro JN, Cueva C, Tamargo A, et al. In Vitro Colonic Fermentation of Saponin-Rich Extracts from Quinoa, Lentil, and Fenugreek. Effect on Sapogenins Yield and Human Gut Microbiota. J Agric Food Chem. 2020;68(1):106–116. doi:10.1021/acs.jafc.9b05659
El Hazzam K, Hafsa J, Sobeh M, et al. An Insight into Saponins from Quinoa (Chenopodium quinoa Willd): A Review. Molecules. 2020;25(5):E1059. Published 2020 Feb 27. doi:10.3390/molecules25051059
Rodríguez-Hernández D, Barbosa LCA, Demuner AJ, Ataide Martins JP, Fischer Nee Heller L, Csuk R. Hederagenin amide derivatives as potential antiproliferative agents. Eur J Med Chem. 2019;168:436–446. doi:10.1016/j.ejmech.2019.02.057
Wu R, Dong S, Cai FF, et al. Active Compounds Derived from Fuzheng Huayu Formula Protect Hepatic Parenchymal Cells from Apoptosis Based on Network Pharmacology and Transcriptomic Analysis. Molecules. 2019;24(2):338. Published 2019 Jan 18. doi:10.3390/molecules24020338
Mireku EA, Mensah AY, Amponsah IK, Danquah CA, Anokwah D, Kwesi Baah M. Antimicrobial pentacyclic triterpenes and glycosides from the stem bark of Cussonia bancoensis. Nat Prod Res. 2020;34(6):859–862. doi:10.1080/14786419.2018.1503262
Fang K, Zhang XH, Han YT, et al. Design, Synthesis, and Cytotoxic Analysis of Novel Hederagenin⁻Pyrazine Derivatives Based on Partial Least Squares Discriminant Analysis. Int J Mol Sci. 2018;19(10):2994. Published 2018 Sep 30. doi:10.3390/ijms19102994
Ma XL, Li WX, Wang D, Lu FP, Dai ZB, Zhang XL. Biosynthesis Analysis of Hederagenin Pathway and Its Construction in Yeast Cells Zhongguo Zhong Yao Za Zhi. 2018;43(9):1844–1850. doi:10.19540/j.cnki.cjcmm.20180307.008
Kim EH, Baek S, Shin D, Lee J, Roh JL. Hederagenin Induces Apoptosis in Cisplatin-Resistant Head and Neck Cancer Cells by Inhibiting the Nrf2-ARE Antioxidant Pathway. Oxid Med Cell Longev. 2017;2017:5498908. doi:10.1155/2017/5498908
