Compendio degli studi più significativi con riferimento a proprietà, assunzione, effetti.

Neuhaus W, Mandikova J, Pawlowitsch R, Linz B, Bennani-Baiti B, Lauer R, Lachmann B, Noe CR. Blood-brain barrier in vitro models as tools in drug discovery: assessment of the transport ranking of antihistaminic drugs. Pharmazie. 2012 May;67(5):432-9.

Sperl G, Gattner J, Deschner J, Wolf M, Proff P, Schröder A, Kirschneck C. Effects of Histamine Receptor Antagonist Cetirizine on Orthodontic Tooth Movement. Biomedicines. 2020 Dec 8;8(12):583. doi: 10.3390/biomedicines8120583.

Bielory L. Allergic inflammation of the anterior surface of the eye. Allergy Asthma Proc. 2020 Nov 1;41(6):449-453. doi: 10.2500/aap.2020.41.200068.

Iriarte Sotés P, Armisén M, Usero-Bárcena T, Rodriguez Fernández A, Otero Rivas M, Gonzalez MT, Meijide Calderón A, Veleiro B; Urtigal, the Galician Group of Interest in Urticaria. Up-Dosing Antihistamines in Chronic Spontaneous Urticaria: Efficacy and Safety. A Systematic Review of the Literature. J Investig Allergol Clin Immunol. 2020 Oct 8:0. doi: 10.18176/jiaci.0649.

Sugiura K, Hirai S, Suzuki T, Usuda T, Kondo T, Azumi T, Masaki S, Yokoi T, Nitta Y, Kamiya S, Ando K, Mori T, Tomita Y. Evaluation of cetirizine hydrochloride-based therapeutic strategy for chronic urticaria. Nagoya J Med Sci. 2008 Aug;70(3-4):97-106.

Abstract.  We investigated the suitability of cetirizine HCl (cetirizine) for the initial treatment of chronic urticaria. A secondary aim was to identify the optimal alternative treatments when switching from this drug to other drugs in patients who are dissatisfied with cetirizine.

Wilkerson H, Datta P, Rewers-Felkins K, Baker T, Hale TW. Maternal Transfer of Cetirizine Into Human Milk. J Hum Lact. 2021 Feb;37(1):135-138. doi: 10.1177/0890334420949847.

Abstract. We suggest that transfer of cetirizine into human milk is minimal and unlikely to pose a significant risk to the breastfeeding infant. This is the first report presenting the transfer of cetirizine in human milk.

Paczkowska M, Mizera M, Lewandowska K, Kozak M, Miklaszewski A, Cielecka-Piontek J. Effects of inclusion of cetirizine hydrochloride in β-cyclodextrin. J Incl Phenom Macrocycl Chem. 2018;91(3):149-159. doi: 10.1007/s10847-018-0808-y.

Abstract.  Following the preparation of inclusion complex of cetirizine (CTZ) and β-cyclodextrin (β-CD), the compound was investigated to assess the possibility of modifying the physicochemical properties (solubility, release, stability, permeability) of CTZ after complexation that are vital for subsequent formulation studies involving the said complex.