Compendium of the most significant studies with reference to properties, intake, effects.

Durán Agüero S, Angarita Dávila L, Escobar Contreras MC, Rojas Gómez D, de Assis Costa J. Noncaloric Sweeteners in Children: A Controversial Theme. Biomed Res Int. 2018 Jan 8;2018:4806534. doi: 10.1155/2018/4806534.

Weihrauch MR, Diehl V. Artificial sweeteners--do they bear a carcinogenic risk? Ann Oncol. 2004 Oct;15(10):1460-5. doi: 10.1093/annonc/mdh256.

Leban I, Rudan-Tasic D, Lah N, Klofutar C. Structures of artificial sweeteners--cyclamic acid and sodium cyclamate with other cyclamates. Acta Crystallogr B. 2007 Jun;63(Pt 3):418-25. doi: 10.1107/S0108768107013961. 

Knowles MA, Jani H, Hicks RM. Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate. Carcinogenesis. 1986 May;7(5):767-74. doi: 10.1093/carcin/7.5.767.

Brower LP. Sodium cyclamate and bladder carcinoma. Science. 1970 Oct 30;170(3957):558. doi: 10.1126/science.170.3957.558. 

Bopp BA, Sonders RC, Kesterson JW. Toxicological aspects of cyclamate and cyclohexylamine. Crit Rev Toxicol. 1986;16(3):213-306. doi: 10.3109/10408448609037465.

Renwick AG, Williams RT. The fate of cyclamate in man and other species. Biochem J. 1972 Oct;129(4):869-79. doi: 10.1042/bj1290869.

Guo W, Li J, Liu Q, Shi J, Gao Y. Tracking the fate of artificial sweeteners within the coastal waters of Shenzhen city, China: From wastewater treatment plants to sea. J Hazard Mater. 2021 Jul 15;414:125498. doi: 10.1016/j.jhazmat.2021.125498. 

Nakama KA, Dos Santos RB, Serpa P, Maciel TR, Haas SE. Organoleptic excipients used in pediatric antibiotics. Arch Pediatr. 2019 Oct;26(7):431-436. doi: 10.1016/j.arcped.2019.09.008. 

Behrens M, Blank K, Meyerhof W. Blends of Non-caloric Sweeteners Saccharin and Cyclamate Show Reduced Off-Taste due to TAS2R Bitter Receptor Inhibition. Cell Chem Biol. 2017 Oct 19;24(10):1199-1204.e2. doi: 10.1016/j.chembiol.2017.08.004.