Dextrins are a group of carbohydrates that are derived from the hydrolysis of starch or glycogen (a polymer of glucose) and usually from many starch sources such as potatoes, wheat or corn.

More than 85% of its molecules have an average molecular mass of about 20,000

They are labeled with the number E1400 in the list of food additives as starches.

Yellow dextrins are used by the food and pharmaceutical industries as thickeners, foam stabilizers, artificial sweetener base.

Wheat dextrin is widely used in the food industry because of its soluble fiber characteristics and its good consistency due to a low viscosity when added to soft foods, water or beverages.

In cosmetic and pharmaceutical formulations, dextrin acts as a moisturizer and binding agent to prevent the various components from dispersing or losing uniformity.

Molecular Formula:     C₁₈H₃₂O₁₆

Molecular Weight: 504.4 g/mol

CAS: 9004-53-9

UNII  2NX48Z0A9G

EC Number:  232-675-4

MDL number  MFCD00081554

PubChem Substance ID   24893590

NACRES  NA.25

Synonims: 

• Fortodex
• Dextrid
• Nutriose
• Caloreen
• (3R,4S,5S,6R)-2-[(2R,3S,4R,5R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Compendium of the most significant studies with reference to properties, intake, effects:

Sumida R, Kishishita S, Yasuda A, Miyata M, Mizote A, Yamamoto T, Mitsuzumi H, Aga H, Yamamoto K, Kawai K. A novel dextrin produced by the enzymatic reaction of 6-α-glucosyltransferase Ⅱ: Practical advantages of the novel dextrin as a food modifier. Biosci Biotechnol Biochem. 2021 Apr 29:zbab076. doi: 10.1093/bbb/zbab076.

Yoplac I, Vargas L, Robert P, Hidalgo A. Characterization and antimicrobial activity of microencapsulated citral with dextrin by spray drying. Heliyon. 2021 Apr 6;7(4):e06737. doi: 10.1016/j.heliyon.2021.e06737.

Emilien CH, Hsu WH, Hollis JH. The Effect of Soluble Fiber Dextrin on Subjective and Physiological Markers of Appetite: A Randomized Trial. Nutrients. 2020 Oct 30;12(11):3341. doi: 10.3390/nu12113341.

Hu Q, Lu Y, Hu F, He S, Xu X, Niu Y, Zhang H, Li X, Su Q. Resistant dextrin reduces obesity and attenuates adipose tissue inflammation in high-fat diet-fed mice. Int J Med Sci. 2020 Sep 20;17(17):2611-2621. doi: 10.7150/ijms.45723.

Mateo-Gallego R , Moreno-Indias I , Bea AM , Sánchez-Alcoholado L , Fumanal AJ , Quesada-Molina M , Prieto-Martín A , Gutiérrez-Repiso C , Civeira F , Tinahones FJ . An alcohol-free beer enriched with isomaltulose and a resistant dextrin modulates gut microbiome in subjects with type 2 diabetes mellitus and overweight or obesity: a pilot study. Food Funct. 2021 Apr 21;12(8):3635-3646. doi: 10.1039/d0fo03160g.

Ferguson EL, Naseer S, Powell LC, Hardwicke J, Young FI, Zhu B, Liu Q, Song B, Thomas DW. Controlled release of dextrin-conjugated growth factors to support growth and differentiation of neural stem cells. Stem Cell Res. 2018 Dec;33:69-78. doi: 10.1016/j.scr.2018.10.008.

Zhen Y, Zhang T, Jiang B, Chen J. Purification and Characterization of Resistant Dextrin. Foods. 2021 Jan 18;10(1):185. doi: 10.3390/foods10010185.

Pereira I, Pereira JE, Maltez L, Rodrigues A, Rodrigues C, Oliveira M, Silva DM, Caseiro AR, Prada J, Maurício AC, Santos JD, Gama M. Regeneration of critical-sized defects, in a goat model, using a dextrin-based hydrogel associated with granular synthetic bone substitute. Regen Biomater. 2020 Nov 28;8(1):rbaa036. doi: 10.1093/rb/rbaa036.

Phillips J, Venter JL, Atanasova M, Wesley-Smith J, Oosthuizen H, Emmambux MN, Du Toit EL, Focke WW. Dextrin Nanocomposites as Matrices for Solid Dosage Forms. ACS Appl Mater Interfaces. 2020 Apr 8;12(14):16969-16977. doi: 10.1021/acsami.0c02061.

Silva-Carvalho R, Fidalgo J, Melo KR, Queiroz MF, Leal S, Rocha HA, Cruz T, Parpot P, Tomás AM, Gama M. Development of dextrin-amphotericin B formulations for the treatment of Leishmaniasis. Int J Biol Macromol. 2020 Jun 15;153:276-288. doi: 10.1016/j.ijbiomac.2020.03.019.

Pan Y, Wu Z, Zhang B, Li XM, Meng R, Chen HQ, Jin ZY. Preparation and characterization of emulsion stabilized by octenyl succinic anhydride-modified dextrin for improving storage stability and curcumin encapsulation. Food Chem. 2019 Oct 1;294:326-332. doi: 10.1016/j.foodchem.2019.05.053.

 Chiron E, Varache M, Stokniene J, Thomas DW, Ferguson EL. A physicochemical assessment of the thermal stability of dextrin-colistin conjugates. Sci Rep. 2021 May 19;11(1):10600. doi: 10.1038/s41598-021-89946-2.

Kikusaki S, Takagi K, Shojima T, Saku K, Fukuda T, Oryoji A, Anegawa T, Fukumoto Y, Aoki H, Tanaka H. Prevention of postoperative intrapericardial adhesion by dextrin hydrogel. Gen Thorac Cardiovasc Surg. 2021 Jan 8. doi: 10.1007/s11748-020-01581-2.

Yuan C, Zhan W, Cui B, Yu B, Liu P, Wu Z. Influence of two functional dextrins on the gel properties of kappa-carrageenan. Food Res Int. 2020 Dec;138(Pt A):109666. doi: 10.1016/j.foodres.2020.109666.

Gawałek J, Domian E. Tapioca Dextrin as an Alternative Carrier in the Spray Drying of Fruit Juices-A Case Study of Chokeberry Powder. Foods. 2020 Aug 15;9(8):1125. doi: 10.3390/foods9081125.