Heptapeptide-15 Palmitate is a natural peptide derived from palm, ester of palmitic acid.

The name defines the structure of the molecule

• "Heptapeptide-15". Indicates a chain of seven amino acids linked together, forming a peptide. The "15" refer to a specific sequence or type of heptapeptide.
• "Palmitate". Indicates the presence of an ester formed from palmitic acid. Palmitic acid is a saturated fatty acid with 16 carbon atoms.

Description of the raw materials used in its production.

• Protected Amino Acids. The amino acids used in peptide synthesis are generally protected to avoid undesired reactions.
• Palmitic Acid. A saturated fatty acid.
• Coupling Reagents. Examples include HBTU (Hexafluorophosphate of Benzotriazol-1-yl-oxy Trispyrrolidino Phosphonium) and DIEA (N,N-Diisopropylethylamine).
• Solvents. DMF (Dimethylformamide), DCM (Dichloromethane), etc.

Step-by-step summary of its industrial chemical synthesis process. 

• Peptide Synthesis. Begins with attaching a protected amino acid to a solid resin. Subsequently, the other six protected amino acids are added in sequence, using coupling reagents to form peptide bonds.
• Removal of Protecting Groups. After synthesis, the protecting groups on the amino acids need to be removed, typically using a mixture of TFA (Trifluoroacetic Acid) and water.
• Esterification. The free peptide is then esterified. This can be done by treating the peptide with palmitic acid and a coupling reagent like EDC (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide).
• Purification. May be carried out via high-performance liquid chromatography (HPLC) to separate the desired peptide from impurities.
• Drying. The purified peptide is then dried, typically under vacuum, to remove residual solvents.

What it is used for and where

Cosmetics

Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.

It is used in cosmetics to deliver another peptide, Copper Palmitoyl Heptapeptide-14, to collagen-producing cells.

Its function is as a moisturizing and collagen-stimulating agent to reduce wrinkles and skin lines.

Commercial applications

Anti-aging Agent. Heptapeptide-15 Palmitate is used in skin care products to reduce the appearance of wrinkles and fine lines.

Collagen Stimulant. It helps to stimulate the production of collagen, improving the elasticity and firmness of the skin.

Firming Agent. Used in cosmetic formulations to firm and tone the skin.

Ingredient in Products for Sensitive Skin. It can be used in products for sensitive skin to reduce redness and irritation.

Moisturizing Agent. Used in creams and serums to enhance skin hydration.