Compendium of the most significant studies with reference to properties, intake, effects.

Fallacara A, Busato L, Pozzoli M, Ghadiri M, Ong HX, Young PM, Manfredini S, Traini D. Combination of urea-crosslinked hyaluronic acid and sodium ascorbyl phosphate for the treatment of inflammatory lung diseases: An in vitro study. Eur J Pharm Sci. 2018 Jul 30;120:96-106. doi: 10.1016/j.ejps.2018.04.042.

Deng Q, Huang S, Wen J, Jiao Y, Su X, Shi G, Huang J. PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice. Stem Cell Res Ther. 2020 Apr 3;11(1):143. doi: 10.1186/s13287-020-01638-2.

Okajima LS, Martinez EF, Pinheiro IF, Fonseca Silva AS, Demasi APD. Effect of sodium ascorbyl phosphate on osteoblast viability and differentiation. J Periodontal Res. 2020 Oct;55(5):660-666. doi: 10.1111/jre.12752.

Spiclin P, Homar M, Zupancic-Valant A, Gasperlin M. Sodium ascorbyl phosphate in topical microemulsions. Int J Pharm. 2003 Apr 30;256(1-2):65-73. doi: 10.1016/s0378-5173(03)00063-2.

Fallacara A, Marchetti F, Pozzoli M, Citernesi UR, Manfredini S, Vertuani AS. Formulation and Characterization of Native and Crosslinked Hyaluronic Acid Microspheres for Dermal Delivery of Sodium Ascorbyl Phosphate: A Comparative Study. Pharmaceutics. 2018 Dec 1;10(4):254. doi: 10.3390/pharmaceutics10040254. 

Ruamrak C, Lourith N, Natakankitkul S. Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment. Int J Cosmet Sci. 2009 Feb;31(1):41-6. doi: 10.1111/j.1468-2494.2008.00479.x.

Foco A, Gasperlin M, Kristl J. Investigation of liposomes as carriers of sodium ascorbyl phosphate for cutaneous photoprotection. Int J Pharm. 2005 Mar 3;291(1-2):21-9. doi: 10.1016/j.ijpharm.2004.07.039. 

Fallacara A, Busato L, Pozzoli M, Ghadiri M, Ong HX, Young PM, Manfredini S, Traini D. Co-Spray-Dried Urea Cross-Linked Hyaluronic Acid and Sodium Ascorbyl Phosphate as Novel Inhalable Dry Powder Formulation. J Pharm Sci. 2019 Sep;108(9):2964-2971. doi: 10.1016/j.xphs.2019.04.015.

Segall AI, Moyano MA. Stability of vitamin C derivatives in topical formulations containing lipoic acid, vitamins A and E. Int J Cosmet Sci. 2008 Dec;30(6):453-8. doi: 10.1111/j.1468-2494.2008.00473.x. 

Marra F, Levy JL, Santi P, Kalia YN. In vitro evaluation of the effect of electrotreatment on skin permeability. J Cosmet Dermatol. 2008 Jun;7(2):105-11. doi: 10.1111/j.1473-2165.2008.00372.x. 

Battino M, Ferreiro MS, Armeni T, Politi A, Bompadre S, Massoli A, Bullon P. In vitro antioxidant activities of antioxidant-enriched toothpastes. Free Radic Res. 2005 Mar;39(3):343-50. doi: 10.1080/10715760400023853.

Safety

Elmore AR. Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. Int J Toxicol. 2005;24 Suppl 2:51-111. doi: 10.1080/10915810590953851.