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 | "Description" by AColumn (9309 pt) | 2019-Sep-07 21:07 |
| Evaluation | N. Experts | Evaluation | N. Experts |
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Usnea barbata beard lichen is a washed green or grey lichen found in both Europe and North America.
It has antibiotic properties and is very bitter. It is used against bronchitis, flu, colds, digestive disorders.
Used in the treatment of cancer, it currently has no authoritative medical evidence to confirm its effectiveness.
Among its components, the usnic acid, a component that can also induce toxicity (1), is used in supplements for weight loss, dandruff and more.
The aqueous methanolic extract of Usnea barbata has been successfully used as an antibiotic therapeutic agent against infections caused by Lactococcus garvieae on rainbow trout (2).
The extract has demonstrated antifungal properties at concentrations of 10mg ml-1 against Alternaria alternaria, a parasite ascomycetes fungus that attacks the leaves and damages the crops of about 350 plant species and can induce allergies in humans (3).
References_________________________________
(1) Activation of the Nrf2 signaling pathway in usnic acid-induced toxicity in HepG2 cells. Chen S, Zhang Z, Qing T, Ren Z, Yu D, Couch L, Ning B, Mei N, Shi L, Tolleson WH, Guo L. Arch Toxicol. 2017 Mar;91(3):1293-1307. doi: 10.1007/s00204-016-1775-y.
The role of autophagy in usnic acid-induced toxicity in hepatic cells. Chen S, Dobrovolsky VN, Liu F, Wu Y, Zhang Z, Mei N, Guo L. Toxicol Sci. 2014 Nov;142(1):33-44. doi: 10.1093/toxsci/kfu154.
(2) Therapeutic effects of beard lichen, Usnea barbata extract against Lactococcus garvieae infection in rainbow trout (Oncorhynchus mykiss). Bilen S, Sirtiyah AMA, Terzi E. Fish Shellfish Immunol. 2019 Apr;87:401-409. doi: 10.1016/j.fsi.2019.01.046.
(3) In vitro antifungal activity of some South African medicinal plants AJ Afolayan, DS Grierson, L Kambizi, I Madamombe and PJ Masika South African Journal of Botany 2002, 68: 72–76
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