Compendium of the most significant studies with reference to properties, intake, effects.

Genedy S, Khames A, Hussein A, Sarhan H. Hydralazine HCl rapidly disintegrating sublingual tablets: simple dosage form of higher bioavailability and enhanced clinical efficacy for potential rapid control on hypertensive preeclampsia. Drug Des Devel Ther. 2018 Nov 5;12:3753-3766. doi: 10.2147/DDDT.S173326.

Abstract. This work aims for the preparation of HHC rapidly disintegrating sublingual tablets of higher absorption rate, short onset of action, and higher bioavailability for rapid control on blood pressure (BP) in hypertensive emergencies especially preeclampsia.

Rudnic EM, Kanig JL, Rhodes CT. Effect of molecular structure variation on the disintegrant action of sodium starch glycolate. J Pharm Sci. 1985 Jun;74(6):647-50. doi: 10.1002/jps.2600740613.

Abstract. The effect of variation in the degree of cross-linkage and extent of carboxymethylation on the disintegration and dissolution properties of sodium starch glycolate has been examined. 

Sallal AK, Nimer NA. The intracellular localization of glycolate oxidoreductase in Escherichia coli. FEBS Lett. 1989 Dec 4;258(2):277-80. doi: 10.1016/0014-5793(89)81673-4.

Abstract. Distribution of glycolate oxidoreductase in cell-free extracts of E. coli grown in mineral medium containing sodium glycolate has been studied.

Doijad RC, Manvi FV, Godhwani DM, Joseph R, Deshmukh NV. Formulation and targeting efficiency of Cisplatin engineered solid lipid nanoparticles. Indian J Pharm Sci. 2008 Mar-Apr;70(2):203-7. doi: 10.4103/0250-474X.41456.

Abstract. Sodium glycolate feeding (50 mg/100 g body weight/day) to adult male rats for 7 days resulted in increased activities of glycolate oxidase in liver and lactate dehydrogenase in liver and kidney.

Talwar HS, Murthy MS, Thind SK, Nath R. Sodium glycolate absorption in rat intestine. Biochem Med. 1984 Jun;31(3):311-8. doi: 10.1016/0006-2944(84)90087-5.

Abstract. Absorption of sodium [1-14C]glycolate by rat intestine was studied by using the tissue accumulation technique with everted intestinal rings.