Compendium of the most significant studies with reference to properties, intake, effects.

Jurek I, Szuplewska A, Chudy M, Wojciechowski K. Soapwort (Saponaria officinalis L.) Extract vs. Synthetic Surfactants-Effect on Skin-Mimetic Models. Molecules. 2021 Sep 16;26(18):5628. doi: 10.3390/molecules26185628.

Abstract. Our skin is continuously exposed to different amphiphilic substances capable of interaction with its lipids and proteins. We describe the effect of a saponin-rich soapwort extract and of four commonly employed synthetic surfactants: sodium lauryl sulfate (SLS), sodium laureth sulfate (SLES), ammonium lauryl sulfate (ALS), cocamidopropyl betaine (CAPB) on different human skin models. 

Kim SH, Ko HC, Kim MB, Kwon KS, Oh CK. The Effect of Detergents on the Morphology and Immunomodulatory Activity of Malassezia furfur. Ann Dermatol. 2009 May;21(2):130-5. doi: 10.5021/ad.2009.21.2.130.

Abstract. We studied whether detergents affect the morphology of M. furfur and if the inflammatory cytokine profiles change in the monocytes treated with detergent-treated M. furfur.

Li MH. Survival, mobility, and membrane-bound enzyme activities of freshwater planarian, Dugesia japonica, exposed to synthetic and natural surfactants. Environ Toxicol Chem. 2012 Apr;31(4):843-50. doi: 10.1002/etc.1748.

Abstract. Surfactants are a major class of emerging pollutants widely used in large quantities in everyday life and commonly found in surface waters worldwide. Freshwater planarian was selected to examine the effects of different surfactants by measuring mortality, mobility, and membrane-bound enzyme activities.

Levine LH, Judkins JE, Garland JL. Determination of anionic surfactants during wastewater recycling process by ion pair chromatography with suppressed conductivity detection. J Chromatogr A. 2000 Apr 7;874(2):207-15. doi: 10.1016/s0021-9673(00)00155-2.

 Abstract. A direct approach utilizing ion pairing reversed-phase chromatography coupled with suppressed conductivity detection was developed to monitor biodegradation of anionic surfactants during wastewater recycling through hydroponic plant growth systems and fixed-film bioreactors.