Compendium of the most significant studies with reference to properties, intake, effects.

Milleman KR, Creeth JE, Burnett GR, Milleman JL. A randomized clinical trial to evaluate the stain removal efficacy of a sodium phytate dentifrice formulation. J Esthet Restor Dent. 2018 Mar;30(2):E45-E51. doi: 10.1111/jerd.12355.

Abstract. This study investigated stain removal efficacy of an experimental sodium phytate-containing dentifrice compared to a reference dentifrice.

Pallauf J, Pippig S, Most E, Rimbach G. Supplemental sodium phytate and microbial phytase influence iron availability in growing rats. J Trace Elem Med Biol. 1999 Nov;13(3):134-40. doi: 10.1016/S0946-672X(99)80003-0.

Abstract. Dietary phytate reduced apparent iron absorption in groups II and III. Furthermore hematocrit, transferrin saturation and iron concentration in liver and femur were lowered in rats fed diets with PA, while total and latent iron-binding capacity of plasma increased. Microbial phytase supplementation (groups IV and V) partly counteracted the antinutritive effects of phytic acid on iron availability.

Feng H, Feng G, Wang J, Li X. Effect of sodium phytate on alkaline phosphatase (ALP) activity in intraradical hyphae of AM fungi and development of its extraradical hyphae. Ying Yong Sheng Tai Xue Bao. 2004 Jun;15(6):1009-13.

Abstract. In this paper, a pot experiment with three compartments was installed to study the effect of Na-phytate on the development and metabolic activity of AM fungi.

Schlemmer U, Frølich W, Prieto RM, Grases F. Phytate in foods and significance for humans: food sources, intake, processing, bioavailability, protective role and analysis. Mol Nutr Food Res. 2009 Sep;53 Suppl 2:S330-75. doi: 10.1002/mnfr.200900099.

Abstract. The article gives an overview of phytic acid in food and of its significance for human nutrition. It summarises phytate sources in foods and discusses problems of phytic acid/phytate contents of food tables. Data on phytic acid intake are evaluated and daily phytic acid intake depending on food habits is assessed. 

Bye JW, Cowieson NP, Cowieson AJ, Selle PH, Falconer RJ. Dual effects of sodium phytate on the structural stability and solubility of proteins. J Agric Food Chem. 2013 Jan 16;61(2):290-5. doi: 10.1021/jf303926v.

Abstract. The interaction between sodium phytate and three proteins was studied using solubility experiments and differential scanning calorimetry (DSC) to assess structural stability. Lysozyme, which is positively charged at neutral pH, bound phytate by an electrostatic interaction.