Compendium of the most significant studies with reference to properties, intake, effects.

Tavano L, Muzzalupo R, Cassano R, Trombino S, Ferrarelli T, Picci N. New sucrose cocoate based vesicles: Preparation, characterization and skin permeation studies. Colloids Surf B Biointerfaces. 2010 Jan 1;75(1):319-22. doi: 10.1016/j.colsurfb.2009.09.003.

Abstract. A commercial sucrose cocoate surfactant was used to obtain a new vesicular system for transdermal drug delivery. The preparation, the dimensional and morphological characterizations and the skin permeation profile of these new niosomes were evaluated.

Vucinić-Milanković N, Savić S, Vuleta G, Vucinić S. The physicochemical characterization and in vitro/in vivo evaluation of natural surfactants-based emulsions as vehicles for diclofenac diethylamine. Drug Dev Ind Pharm. 2007 Mar;33(3):221-34. doi: 10.1080/03639040601150179.

Abstract. Two sugar-based emulsifiers, cetearyl alcohol & cetearyl glycoside and sorbitan stearate & sucrose cocoate, known as potential promoters of lamellar liquid crystals/gel phases, were investigated in order to formulate an optimal vehicle for amphiphilic drug - diclofenac diethylamine (DDA). Physico-chemical characterization and study of vehicle's physical stability were performed. 

Ahsan F, Arnold JJ, Meezan E, Pillion DJ. Sucrose cocoate, a component of cosmetic preparations, enhances nasal and ocular peptide absorption. Int J Pharm. 2003 Jan 30;251(1-2):195-203. doi: 10.1016/s0378-5173(02)00597-5.

Abstract. In order to determine its potential utility in enhancing nasal and ocular drug delivery, absorption studies were performed in anesthetized Sprague-Dawley male rats with calcitonin and insulin, two distinct therapeutic peptides.