Compendium of the most significant studies with reference to properties, intake, effects.

Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... & Heldreth, B. (2018). Safety assessment of tocopherols and tocotrienols as used in cosmetics. International journal of toxicology, 37(2_suppl), 61S-94S.

Abstract. The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 14 tocopherols and tocotrienols and concluded these ingredients are safe as used in cosmetics....Tocopheryl acetate was (1) delivered in a triglyceride oil (caprylic/capric acid triglyceride); (2) surfactant-solubilized in water (PPG-26-buteth-26 and polyethylene glycol [PEG]-40 hydrogenated castor oil)...

Omelyanchuk, P. A., Vilinskaya, S. V., Timchenko, L. D., Rzepakovsky, I. V., Vakulin, V. N., & Sisonenko, M. N. (2014). Regenerating composition for skin care. Type: patent for invention Patent number: RU 2504359 C1 Patent Office: Russia Year of publication: 2014 Application number: 2012149562/15 Registration date: 11/21/2012Publication date: 1/20/2014 Patent holders: StavStandard Limited Liability Company

Abstract. .. invention relates to cosmetology and represents regenerating composition for skin care which contains regulator pH-triethanolamine, BAA, base Salcare SC80, cyclomethicone DC345, preservative, odorant, water, which is characterised by the fact, that as biologically active additive it contains protein substance from quail egg and antioxidant, and base includes UV-filter, olive oil, glycerin, emulsifier Solubilisant LRL preservative Sharomix MCI an purified water, and components in composition are in specified ratio in wt %....Solubilisant LRI - PPG-26-Buteth-26 (and) PEG-40 Hydrogenated Castor Oil. …

Liu, Z., Liao, T., Yang, N., Ding, L., Li, X., Wu, P., & Wang, P. (2021). Interventional Efects of the Topical of “Sanse Powder” Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis. Frontiers in Pharmacology, 2367.

Abstract. Our recent research is dedicated to finding effective drugs for the treatment of knee osteoarthritis (KOA) from traditional Chinese medicine and trying to make full use of modern science and technology to uncover the mechanisms and targets behind them....Briefly, firstly, the screened emulsifiers (tween-80, span-80), co-emulsifiers (octyldodecanol,PPG-26-Buteth-26), and BHT were mixed... 

STUDY OF COMPOSITION OF FRAGRANCE COMPOSITIONS AND ITS SOLUBILISATION IN SOLUTIONS OF NON-IONIC PAV Ivanova D.M., Bogdanova SA,Tuntseva S.N. - Vestnik Technologicheskogo Kazan National Research Technological University ISSN: 1998-7072

Abstract. This paper investigates solubilization of perfume compositions in alcohol-aqueous solutions in the presence of two solubilizers Eumulgin CO 410 (PEG-40 Hydrogenated Castor Oil) and Solubilizant LRI (a mixture of PEG-40 Hydrogenated Castor Oil and PPG-26-Buteth-26).

Johnson Jr, W. (2000). Final report on the safety assessment of PPG-12-Buteth-16, PPG-9-Buteth-12, PPG-26-Buteth-26, and PPG-28-Buteth-35. International Journal of Toxicology, 19, 47-67.

Abstract. Absent any data on the dermal absorption of a low-molecular-weight PPG Buteth, or actual data on skin irritation and sensitization, it was concluded that the available data are insufficient to support the safety of PPG-9-Buteth-12 or PPG-12-Buteth-16 in cosmetic products. Based on the available data, PPG-26-Buteth-26 and PPG-28-Buteth-35 are considered safe as used in cosmetic products.