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 | "Descrizione" by A_Partyns (12876 pt) | 2019-Sep-04 21:20 |
| Evaluation | N. Experts | Evaluation | N. Experts |
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| 1 | 6 | ||
| 2 | 7 | ||
| 3 | 8 | ||
| 4 | 9 | ||
| 5 | 10 |
Thuja occidentalis (Western red cedar)) and Thuja orientalis belong to the Cupressaceae family, they are evergreen trees originating from North America and East Asia.
Thuja is an oil used in alternative medicine and phytotherapy to treat scurvy, cystitis, rheumatism, cancer.
One of its components, alpha-thujone, a monoterpene that can easily penetrate the blood-brain barrier, has shown positive therapeutic effects against cancer. Alfa-thujone exerts proapoptotic and anti-invasive effects on cells confirming the potential for the treatment of glioblastoma multiforme (1).
In the essential oil of Thuja occidentalis there are terpenes such as Alpha-pinene, alpha cedrol, terpinolene, limonene (2).
In this study, leaf extract from Thuja orientalis showed a clear inhibition of angiogenesis in vivo and in vitro in lung cancer cells, thus demonstrating anti-cancer properties (3).
It is used in cosmetics and body cleansers.
References__________________________________________________________
(1) Therapeutic potential of monoterpene α-thujone, the main compound of Thuja occidentalis L. essential oil, against malignant glioblastoma multiforme cells in vitro. Pudełek M, Catapano J, Kochanowski P, Mrowiec K, Janik-Olchawa N, Czyż J, Ryszawy D. Fitoterapia. 2019 Apr;134:172-181. doi: 10.1016/j.fitote.2019.02.020.
(2) Short Communication: Evaluation of the chemical composition of essential oil of Thuja occidentalis leaves grown in Peshawar, Pakistan by gas chromatography mass spectrometry. Qureshi MN, Siddique M, Rahman IU, Kanwal F. Pak J Pharm Sci. 2016 Nov;29(6):2105-2107.
(3) Non-toxic and non teratogenic extract of Thuja orientalis L. inhibited angiogenesis in zebra fish and suppressed the growth of human lung cancer cell line. R EB, Jesubatham PD, V M BG, S V, S S. Biomed Pharmacother. 2018 Oct;106:699-706. doi: 10.1016/j.biopha.2018.07.010.
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