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Dibasic sodium phosphate - Sodium dibasic phosphate
"Descrizione"
by CarPas (5225 pt)
2022-Aug-14 18:29

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Dibasic sodium phosphate or Sodium dibasic phosphate is a chemical compound, one of the hydrated salts of sodium acid generated from phosphoric acid.

It appears as a white powder, soluble in water and the aqueous solution is weakly alkaline.

What it is used for and where

Medical

Together with Monobasic Sodium Phosphate, it is used in both adults and children in evacuative solutions such as disposable enemas for the treatment of constipation, as a pH regulator and saline laxative, for the treatment of acute and chronic constipation and also for colon cleansing as a preparation for surgical procedures (1). These chemical compounds increase water content and stool volume, creating a rectal distension effect. The required effect is usually produced within about 5 minutes.

Dibasic sodium phosphate is also used as therapy in lead poisoning.

Dentistry

The incorporation of dibasic sodium phosphate as a buffering agent in the composition of the mineral trioxide aggregate is recognised as one of the solutions to improve its properties, reduce time and achieve a diametral tensile strength of 4.9 MPa at the initial 6-hour period.(2). Nucleating agent.

Human nutrition

The addition of dibasic sodium phosphate to meat increases the pH value and ionic strength of the meat, improving water retention and the overall yield of the final product.

Baking agent to prevent oxidation, emulsifier

Animal feed

Dibasic sodium phosphate is used for oral phosphorus supplementation in animal feed. In Qianbei-Pockmarked goats suffering from a disorder referred to as 'Ruanguzheng's disorder', disodium hydrogen phosphate supplementation prevented and cured the disorder (3).

For more information:

Disodium hydrogen phosphate studies

Typical commercial product characteristics Sodium Phosphate, Dibasic

AppearanceWhite crystal or powder,
pH8.8~9.2
Boiling Point
158ºC at 760 mmHg
Melting Point
243-245°C
Density1.064 g/mL at 20°C
PSA93.23000
Vapor density
4.9
Water Solubility
>=10 g/100 mL at 20ºC
Water insoluble
≤ 0.4%
Loss on drying
≤ 5.0%
Fluoride≤0.002%
Chloride≤ 0.06%
Sulphate≤ 0.2%
Arsenic≤ 0.0003%
Heavy Metals (As Pb)≤ 0.001%



Price

1 kg         €168.00

12 kg       €1,010.00

  • Molecular Formula   HO4PNa2  o  HNa2O4P  o  Na2HPO4 
  • Molecular Weight     141.959
  • Exact Mass    141.940781
  • CAS  7558-79-4
  • UNII    22ADO53M6F
  • EC Number   231-448-7
  • DSSTox Substance ID  DTXSID1026039
  • IUPAC  disodium;hydrogen phosphate
  • InChI=1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
  • InChl Key      BNIILDVGGAEEIG-UHFFFAOYSA-L
  • SMILES   OP(=O)([O-])[O-].[Na+].[Na+]
  • MDL number    MFCD00003496
  • PubChem Substance ID    329824633
  • ChEBI  34683
  • FEMA        2398
  • ICSC    1129
  • RTECS   WC4500000
  • UN    3082
  • eCl@ss     38070211
  • NACRES NA.21

Synonyms

  • Disodium Phosphate Dibasic
  • Disodium hydrogenorthophosphate
  • Disodium hydrogen phosphate
  • Sodium phosphate dibasic
  • DSHP 

References_____________________________________________________________

(1) Osgard E, Jackson JL, Strong J. A randomized trial comparing three methods of bowel preparation for flexible sigmoidoscopy. Am J Gastroenterol. 1998 Jul;93(7):1126-30. doi: 10.1111/j.1572-0241.1998.00342.x

(2) Ghasemi N, Rahimi S, Lotfi M, Solaimanirad J, Shahi S, Shafaie H, Salem Milani A, Shakuie S, Zand V, Abdolrahimi M. Effect of Mineral Trioxide Aggregate, Calcium-Enriched Mixture Cement and Mineral Trioxide Aggregate with Disodium Hydrogen Phosphate on BMP-2 Production. Iran Endod J. 2014 Summer;9(3):220-4. 

(3) Shen X, Chi Y, Huo B, Xiong K. Studies on phosphorus deficiency in the Qianbei-Pockmarked goat. Asian-Australas J Anim Sci. 2019 Jun;32(6):896-903. doi: 10.5713/ajas.18.0622.

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