Compendium of the most significant studies with reference to properties, intake, effects.

Disapio A, Fridd P. Silicones: use of substantive properties on skin and hair. Int J Cosmet Sci. 1988 Apr;10(2):75-89. doi: 10.1111/j.1467-2494.1988.tb00004.x.

Abstract. Summary Silicones have been incorporated in personal care products since the 1950s. Initially used in skin care products, and more recently in hair care applications, silicones are recognized for their lubricating properties and for the characteristic soft smooth feel they impart. With recent advances in silicone technology, these fluids can also provide substantivity and durability. Resinous silicones such as trimethylsiloxysilicate act as effective substantivity additives when combined with dimethyl silicone in skin care formulations. In tests evaluating the number of wash cycles required to penetrate a silicone barrier, resistance to removal increases markedly as the proportion of resinous silicone to dimethyl silicone is increased. This improvement is related directly to decreased solubility of the resin.

Ogihara, H., Katayama, T., & Saji, T. (2011). One-step electrophoretic deposition for the preparation of superhydrophobic silica particle/trimethylsiloxysilicate composite coatings. Journal of colloid and interface science, 362(2), 560-566.

Abstract. SiO2 particle/silicone resin (trimethylsiloxysilicate (TMSS)) composite coatings were prepared by electrophoretic deposition (EPD), and their wettability was examined. SiO2 coatings prepared by EPD baths without TMSS were hydrophilic, while superhydrophobicity was observed for SiO2/TMSS composite coatings. IR spectra and EDS analyses revealed that not only SiO2 particles but also TMSS electrophoretically moved toward a cathode; as a result, hydrophilic SiO2 particles turned into superhydrophobic composite coatings by one-step EPD. SEM and AFM images of the superhydrophobic SiO2/TMSS composite coatings showed the presence of both nanometer- and micrometer-sized roughness in their surfaces. Particle size of SiO2 had a great influence on the wettability of the composite coatings. The superhydrophobic SiO2/TMSS composite coatings showed excellent water repellency; they repelled running water continuously. In addition, by controlling the amount of deposited SiO2 particles and TMSS, transparent superhydrophobic SiO2/TMSS composite coatings were prepared.

Geuli, O., & Mandler, D. (2018). The synergistic effect of benzotriazole and trimethylsiloxysilicate towards corrosion protection of printed Cu-based electronics. Corrosion Science, 143, 329-336.

Abstract. The development of printed electronics has gained much attention as an alternative for conventional metal-based electronics, mainly due to the ability to print electronic circuits on plastics and by much cheaper means as compared with conventional microelectronics. Here we report on a single stage formation of a highly corrosion resistance coating with hydrophobic properties on printed-Cu nanoparticles. Our method is based on the synergistic effect of benzotriazole (BTA) as corrosion inhibitor and trimethylsiloxysilicate (TMS) as hydrophobic component. Printed-Cu coated with such TMS/BTA layer exhibited excellent corrosion resistance in 3.5% NaCl solution, reducing the dissolution of Cu into soluble species by one order of magnitude.

Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D., ... & Andersen, F. A. (2013). Safety assessment of silylates and surface-modified siloxysilicates. International journal of toxicology, 32(3_suppl), 5S-24S.

Abstract. The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of silica silylate, silica dimethyl silylate, trimethylsiloxysilicate, and trifluoropropyldimethyl/trimethylsiloxysilicate as used in cosmetics. These silylates and surface-modified siloxysilicates function in cosmetics as antifoaming agents, anticaking agents, bulking agents, binders, skin-conditioning agents—emollient, skin-conditioning agents—occlusive, slip modifiers, suspension agents—nonsurfactant, and viscosity increasing agents—nonaqueous. The Expert Panel reviewed the available animal and clinical data as well as information from a previous CIR safety assessment of amorphous silica. The CIR Expert Panel concluded that silica silylate, silica dimethyl silylate, trimethylsiloxysilicate, and trifluoropropyldimethyl/trimethylsiloxysilicate are safe as used when formulated and delivered in the final product not to be irritating or sensitizing to the respiratory tract.