Serotonin (5-hydroxytryptamine or 5HT) is a hormone found in the pineal gland, the central nervous system, the digestive tract and platelets. It is a neurotransmitter that regulates important functio ...

Read the full Tiiip

(Send your comment)

Serotonin (5-hydroxytryptamine or 5HT) is a hormone found in the pineal gland, the central nervous system, the digestive tract and platelets.

It is a neurotransmitter that regulates important functions such as:

• mood
• sleep
• blood vessels

The level and the system of serotonin are different between uommini and women in which the receptors are more consistent.

There are numerous studies on serotonin and on the effects linked to the contrast of depression (1), to diseases related to stress such as psoriasis (2) or hypertension (3).

Small amounts of serotonin can also be found in the peel of the hazelnut (4).

Serotonin studies

Molecular Formula: C₁₀H₁₂N₂O

Molecular Weight: 176.219 g/mol

UNII: 333DO1RDJY

CAS: 50-67-9

EC Number: 200-058-9

FEMA Number:

Synonyms:

• 5-Hydroxytryptamine
• 3-(2-Aminoethyl)-1H-indol-5-ol
• Hippophain
• Antemoqua
• Substance DS
• Substanz DS
• Enteramine
• 5-HT
• Antemovis
• Serotonine
• Thrombocytin
• Thrombotonin
• 3-(.beta.-Aminoethyl)-5-hydroxyindole
• 5-Hydroxy-3-(.beta.-aminoethyl)indole
• 5-Hydroxytryptamine, 5-HT, Enteramine
• 1H-Indol-5-ol, 3-(2-aminoethyl)-
• 5-Hta
• Tryptamine, 5-hydroxy-
• 3-(2-Aminoethyl)indol-5-ol
• Enteramin
• Indol-5-ol, 3-(2-aminoethyl)-

References_________________________________________

(1)  Serotonin-norepinephrine reuptake inhibitor therapy in late-life depression is associated with increased marker of bone resorption.
Shea ML, Garfield LD, Teitelbaum S, Civitelli R, Mulsant BH, Reynolds CF 3rd, Dixon D, Doré P, Lenze EJ.

(2) Serotonergic drugs--a possible role in the treatment of psoriasis?
Thorslund K, Nordlind K.
Drug News Perspect. 2007 Oct;20(8):521-5. Review.

(3) One-Month Serotonin Infusion Results in a Prolonged Fall in Blood Pressure in the Deoxycorticosterone Acetate (DOCA) Salt Hypertensive Rat.
Davis RP, Szasz T, Garver H, Burnett R, Tykocki NR, Watts SW.
ACS Chem Neurosci. 2013 Jan 16;4(1):141-8. doi: 10.1021/cn300114a. 

(4) Investigation of serotonin, free and protein-bound tryptophan in Turkish hazelnut varieties and effect of roasting on serotonin content.  Taş NG, Yılmaz C, Gökmen V.  Food Res Int. 2019 Jun;120:865-871. doi: 10.1016/j.foodres.2018.11.051

Sign up to vote this object, vote his reviews and to contribute to Tiiips.Evaluate