Aluminum Sesquichlorohydrate è un composto chimico inorganico.

A cosa serve e dove si usa

Cosmetica

Antitraspirante. Controlla sia il sudore che l'odore del corpo evitando che il sudore arrivi nello strato corneo con un'azione battericida preventiva. Nel caso in cui il sudore sia appena arrivato in superficie epidermica, crea un agglomerato temporaneo sulla ghiandola sudoripare che verrà rimosso con il lavaggio.

Astringente. Questo ingrediente esercita un effetto diretto sulla pelle restringendo i pori dilatati contraendo le cellule dello strato corneo e rimuovendo l'olio superfluo.

Agente deodorante. Quando in formulazioni cosmetiche sono inserite sostanze che emanano un odore sgradevole (tipici esempi sono il metil mercaptano e l'idrogeno solforato derivati dall'aglio) i deodoranti attenuano o cancellano le esalazioni sgradevoli.

EC number 234-310-4

CAS: 11089-92-2

Sicurezza

L'alluminio può interferire con diversi processi biologici (stress ossidativo cellulare, metabolismo del calcio, ecc.), quindi può indurre effetti tossici in diversi organi e sistemi ed il sistema nervoso è il principale bersaglio della sua tossicità.

E' da considerare con attenzione il rischio del cumulo di assunzione di alluminio, che non può essere escluso in quanto questo ingrediente può trovarsi sia in prodotti cosmetici che in prodotti alimentari a largo consumo come pane, vari prodotti da forno (1).

Bibliografia_________________________________________________________________________

 (1)Tietz, T., Lenzner, A., Kolbaum, A.E. et al. Aggregated aluminium exposure: risk assessment for the general population. Arch Toxicol 93, 3503–3521 (2019). https://doi.org/10.1007/s00204-019-02599-z

 Abstract. Aluminium is one of the most abundant elements in earth’s crust and its manifold uses result in an exposure of the population from many sources. Developmental toxicity, effects on the urinary tract and neurotoxicity are known effects of aluminium and its compounds. Here, we assessed the health risks resulting from total consumer exposure towards aluminium and various aluminium compounds, including contributions from foodstuffs, food additives, food contact materials (FCM), and cosmetic products. For the estimation of aluminium contents in foodstuff, data from the German “Pilot-Total-Diet-Study” were used, which was conducted as part of the European TDS-Exposure project. These were combined with consumption data from the German National Consumption Survey II to yield aluminium exposure via food for adults. It was found that the average weekly aluminium exposure resulting from food intake amounts to approx. 50% of the tolerable weekly intake (TWI) of 1 mg/kg body weight (bw)/week, derived by the European Food Safety Authority (EFSA). For children, data from the French “Infant Total Diet Study” and the “Second French Total Diet Study” were used to estimate aluminium exposure via food. As a result, the TWI can be exhausted or slightly exceeded—particularly for infants who are not exclusively breastfed and young children relying on specially adapted diets (e.g. soy-based, lactose free, hypoallergenic). When taking into account the overall aluminium exposure from foods, cosmetic products (cosmetics), pharmaceuticals and FCM from uncoated aluminium, a significant exceedance of the EFSA-derived TWI and even the PTWI of 2 mg/kg bw/week, derived by the Joint FAO/WHO Expert Committee on Food Additives, may occur. Specifically, high exposure levels were found for adolescents aged 11–14 years. Although exposure data were collected with special regard to the German population, it is also representative for European and comparable to international consumers. From a toxicological point of view, regular exceedance of the lifetime tolerable aluminium intake (TWI/PTWI) is undesirable, since this results in an increased risk for health impairments. Consequently, recommendations on how to reduce overall aluminium exposure are given.