E301 (Sodium Ascorbate) is a chemical compound, a salt derived from ascorbic acid (Vitamin C).

What it is used for and where

Food

It is an antioxidant used mostly in the food sector where it is labeled with the number E301 in food additives.

Medical

In dentistry it is used in teeth whitening (1) and as a binder against micro-infiltration (2).

Cosmetics

Antioxidant agent. Ingredient that counteracts oxidative stress and prevents cell damage. Free radicals, pathological inflammatory processes, reactive nitrogen species and reactive oxygen species are responsible for the ageing process and many diseases caused by oxidation.

"Sodium ascorbate studies"

Molecular Formula: C₆H₇O₆Na C₆H₇NaO₆

Molecular Weight: 198.106 g/mol

CAS: 134-03-2  58657-35-5

EC Number: 205-126-1

UNIII: S033EH8359

Synonyms:

• L-Ascorbic acid sodium salt
• L-Ascorbic acid, monosodium salt
• Vitamin C sodium
• Monosodium L-ascorbate
• E301
• Ascorbicin
• Ascorbic acid sodium salt
• Sodascorbate
• Ascorbin
• Cebitate
• Ascorbic acid sodium derivative
• Aminofenitrooxon
• Sodium derivative of 3-oxo-L-gulofuranolactone
• Natrii ascorbas
• sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
• Sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
• sodium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate

References____________________________________________________________________

(1) Effect of sodium ascorbate on the bond strength of silorane and methacrylate composites after vital bleaching.
Güler E, Gönülol N, Özyilmaz ÖY, Yücel AÇ.
Braz Oral Res. 2013 Jul-Aug;27(4):299-304.

(2) Effect of sodium ascorbate on resin bonding to sodium perborate-bleached dentin.
Yoon M, Burrow MF, Wong R, Parashos P.
Oper Dent. 2014 Jan-Feb;39(1):98-106. doi: 10.2341/12-516-L.

Effective application duration of sodium ascorbate antioxidant in reducing microleakage of bonded composite restoration in intracoronally-bleached teeth.
Park JY, Kwon TY, Kim YK.
Restor Dent Endod. 2013 Feb;38(1):43-7. doi: 10.5395/rde.2013.38.1.43.