Glycerophosphoinositol Choline is a semi-synthetic chemical compound, the salt of choline and glycerophosphoinositol 

What it is used for and where

Medical

It is used in the treatment of skin xerosis and irritative and allergic dermatitis, psoriasis, is well tolerated and has a sebum-balancing and emollient action on the stratum corneum (1). In an efficacy and safety comparison with other emollients, Glycerophosphoinositol Choline was found to be slightly more effective in reducing the symptoms of atopic dermatitis than other commercially available emollients (2).

Cosmetics

Skin protectant. It creates a protective barrier on the skin to defend it from harmful substances, irritants, allergens, pathogens that can cause various inflammatory conditions. These products can also improve the natural skin barrier and in most cases more than one is needed to achieve an effective result.

• Molecular Formula  C₁₄H₃₂NO₁₂P      C₉H₁₈O₁₁P.C₅H₁₄NO
• Molecular Weight  437.38    
• CAS  425642-32-6 
• UNII    3W4V4N5240
• EC Number  447-400-5 

References_____________________________________________________________________

(1) Motolese, A. and Simonelli, M., 2008. Effect of glycerophosphoinositol salt of choline 1% cream on mild-to-moderate inflammatory and allergic dermatitis. J Istitut o Dermatologico San Gallicano, 10, pp.135-140.

(2) Marko, M. and Pawliczak, R., 2022. Real-life efficiency and safety comparison study of emollient ointment based on glycerophosphoinositol (GPI) salt of choline and other emollient products in patients with atopic dermatitis. Journal of Dermatological Treatment, 33(2), pp.999-1010.