Silanediol Salicylate is an organic compound used in various cosmetic and skincare products, known for its anti-inflammatory and soothing properties. This ingredient is particularly valued for its ability to improve skin health by reducing redness and irritation and for its protective action against environmental damage. Silanediol Salicylate combines the properties of salicylate, a derivative of salicylic acid, with those of silanols, organic silicon compounds known for their moisturizing and regenerative properties.

The name describes the structure of the molecule:

Silanediol indicates the presence of a silanediol group in the molecule. Silanediol is an organic compound containing the functional group -Si(OH)₂.

Salicylate indicates the presence of salicylic acid or its derivative, salicylate, in the molecule. Salicylic acid is known for its exfoliating and anti-inflammatory properties on the skin.

Chemical Industrial Synthesis Process

The production of Silanediol Salicylate, used in cosmetics for its anti-inflammatory, moisturizing, and UV protective properties, follows a chemical process that involves organic synthesis and the reaction of salicylate with silicon-based compounds. 

• Synthesis. Production begins with the synthesis of the necessary chemical precursors, including salicylate and silanediol or its derivatives. These compounds can be synthesized through specific chemical reactions that require catalysts and controlled reaction conditions.
• Reaction. The key step is the reaction of salicylate with silanediol or derivatives to form Silanediol Salicylate. This reaction may require the use of catalysts and specific conditions of temperature and pH to favor the formation of the desired product.
• Purification. After the reaction, the product may contain impurities or by-products that need to be removed. Purification is carried out using techniques such as crystallization, vacuum distillation, or chromatography to obtain a pure final product.
• Quality Control. The purified Silanediol Salicylate undergoes rigorous quality control checks to verify its purity, chemical structure, and efficacy. These tests can include spectroscopic analyses, chromatographic analyses, and in vitro efficacy tests to confirm the anti-inflammatory and protective properties.

Form and Color. Silanediol Salicylate appears as a viscous liquid ranging from clear to light yellow in color.

What it is for and where

The function of this compound can vary depending on the context in which it is used. Silanediol salicylate may be used in cosmetics and skincare products for its exfoliating, soothing, and anti-inflammatory properties. It can help improve skin texture, reduce inflammation, and prevent the formation of comedones and blackheads.

Cosmetics - INCI Functions

Skin conditioning agent - Emollient. Emollients have the characteristic of enhancing the skin barrier through a source of exogenous lipids that adhere to the skin, improving barrier properties by filling gaps in intercorneocyte clusters to improve hydration while protecting against inflammation. In practice, they have the ability to create a barrier that prevents transepidermal water loss.  Emollients are described as degreasing or refreshing additives that improve the lipid content of the upper layers of the skin by preventing degreasing and drying of the skin. The problem with emollients is that many have a strong lipophilic character and are identified as occlusive ingredients; they are oily and fatty materials that remain on the skin surface and reduce transepidermal water loss. In cosmetics, emollients and moisturisers are often considered synonymous with humectants and occlusives.

Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.

In hair care products, this peptide can help promote hair growth and prevent loss (1).

References_____________________________________________________________________

(1) Carlos, R. M. D., & Sarruf, F. D. (2023). Comparative study of the effectiveness of intradermotherapy associated or not with microneedling and topical solution in reducing hair loss in men with androgenetic alopecia. Surgical & Cosmetic Dermatology, 15, e20230197.

Abstract. Introduction: Androgenetic alopecia impacts patients psychologically. Androgenetic alopecia is an androgen-dependent condition characterized by hair follicles miniaturization, shortened anagen phase, and prolonged telogen phase. The increasing search for hair therapies to improve this condition leads to the need for robust methods to compare the effectiveness of treatments, such as standardized photographs and clinical evaluation.  Objective: This study comparatively assessed the efficacy of intradermotherapy associated or not with microneedling and application of sterile topical solution whose active components are Octapeptide-2, Copper tripeptide-1, Chondrus crispus extract, and Silanediol salicylate. ...Conclusion: The therapeutic association of intradermotherapy with microneedling followed by topic treatment was significantly more effective in improving male hair loss compared to control.