Hibiscus Esculentus Seed Extract, or okra fruit extract, is derived from the seeds of the okra plant. This extract is rich in vitamins such as vitamin C and various antioxidants, which are beneficial for skin health. 

The name describes the structure of the molecule:

• Hibiscus Esculentus is the scientific name for okra, also known as gumbo. It is a plant native to Africa and widely cultivated in warm climates for its edible fruits.
• Seed Extract indicates that the product is a concentrated form obtained from processing the seeds of Hibiscus Esculentus.

Industrial Production Process

• Harvesting. The seeds are collected after the fruits have fully matured and dried.
• Cleaning and preparation of seeds. The seeds are cleaned to remove external impurities and debris.
• Maceration. The cleaned seeds are ground or crushed to facilitate the extraction of active compounds.
• Solvent extraction. The ground seeds are immersed in a suitable solvent (such as ethanol, methanol, or water) to extract the active ingredients.
• Heating and agitation. The extraction mixture is heated and agitated to enhance the efficiency of extraction.
• Filtration. After extraction, the liquid is filtered to separate out the solid seed residues.
• Vacuum concentration. The filtrate is concentrated using vacuum evaporators to reduce volume and increase the concentration of extracted compounds.
• Purification. The concentrated extract may be further purified using techniques like chromatography to isolate and purify specific compounds.
• Sterilization. The final extract is sterilized, for example, through heat treatment or filtration, to ensure microbiological safety.

What it is used for and where

It is known for its moisturizing and soothing properties and is used in cosmetics to improve skin texture and for its anti-aging capabilities. Okra extract helps promote cell regeneration and can improve skin elasticity, making it smoother and more youthful. It is often included in formulations for creams, serums, and facial masks, where it contributes to increased hydration and combating the signs of aging.

Cosmetics - INCI Functions

• Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.

CAS   91723-07-8

EC   294-510-2

Main uses and benefits of Hibiscus Esculentus Seed Extract

Moisturizing Properties. This extract is rich in essential fatty acids, which help to keep the skin hydrated, deeply nourishing it and improving its elasticity.

Antioxidant Effects. It contains natural antioxidants that help protect the skin from free radical damage and combat signs of aging.

Promoting Skin Health. The omega-6 fatty acids in okra oil support cell regeneration and can improve the appearance of damaged or irritated skin.

Soothing Effects. It can help to soothe skin irritations and reduce redness, making it suitable for sensitive or inflamed skin.

Strengthening the Skin Barrier. The extract helps to strengthen the skin barrier, protecting the skin from harmful external agents and improving its ability to retain moisture.

Versatile Applications. It can be used in a variety of skincare products, including creams, lotions, serums, and hair products, thanks to its richness in nutrients and skin benefits.

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Hibiscus or Okra (Hibiscus Esculentus) belongs to the Malvaceae family and it is an evergreen plant which is used as a hedge or as a single plant both outdoors in full soil, and indoors in pots.

Hibiscus is a great source of vitamins C and K, folate, and magnesium. It also contains antioxidants that help protect the body against free radicals.

The high dietary fiber content in hibiscus aids in digestion and maintains a healthy gut. These fibers can also help regulate blood sugar levels.

Hibiscus is low in calories and rich in fiber, which is beneficial for heart health. The fibers help reduce cholesterol levels, and the plant contains potassium, important for maintaining healthy blood pressure.

Concerns Associated with Hibiscus

Oxalates. Hibiscus is high in oxalates, which can be a concern for people prone to kidney stones. Consuming hibiscus can contribute to the formation of these stones in susceptible individuals.

FODMAPs. Hibiscus contains fructans, a type of FODMAP, which can cause digestive discomfort in people with irritable bowel syndrome (IBS).

Vitamin K Content. Rich in vitamin K, hibiscus may interact with blood-thinning medications like warfarin. Patients taking such medications should monitor their hibiscus intake to prevent potential effects.

Studies

From the species Hibiscus syriacus have been isolated some interesting components for human health, including: vitexin, isovitexin, quercetin, kaempferol and rutin (1) and also molecules such as phytosterols, phenolic compounds and flavonoids all with antioxidant properties and with the ability to improve the glycemic profile (2). Another interesting application concerns the ability of Hibiscus extract to treat anal fissure (3)

The preventive action of Hibiscus okra ethanolic extract against liver damage was evaluated in rodents in this complex study, which found significant dose-dependent hepatoprotection. The hepatoprotective and antioxidant activities of the extract were comparable to standard silymarin. These findings were supported by histological evaluation of liver biopsy. The ability of okra extract to protect against chemically induced liver damage may be attributed to its potent antioxidant property (4).

Cultivation

When grown indoors, it should be placed in a very bright location. It withstands adverse climatic conditions well but needs to be fertilized often. It blooms between spring and summer.

References_____________________________________________________________________

(1) Wei Q, Ji XY, Xu F, Li QR, Yin H. Chemical Constituents from Leaves of Hibiscus syriacus and Their α-Glucosidase Inhibitory Activities. Zhong Yao Cai. 2015 May;38(5):975-9. 

Abstract. Objective: To study the chemical constituents from Hibiscus syriacus leaves and their α-glucosidase inhibitory activities....Conclusion: All the compounds are isolated from the leaves of Hibiscus syriacus for the first time. Taking acarbose as positive control, the α-glucosidase inhibitory activities of 15 compounds were evaluated. Compounds 7 and 9 have shown strong α-glucosidase inhibitory activities with IC50 of 39.03 ± 0.38 and 32.12 ± 0.62 mg/L, inhibition ratio of 94.95% and 97.15%, respectively.

 (2) Akbari F, Shahinfard N, Mirhoseini M, Shirzad H, Heidarian E, Hajian S, Rafieian-Kopaei M. Impacts of Hibiscus esculentus extract on glucose and lipid profile of diabetic rats. J Nephropharmacol. 2015 May 19;5(2):80-85.

Abstract. Introduction:Hibiscus esculentus is capable to produce various molecules including phenolic and flavonoid compounds, phytosteroids with antioxidant property. Therefore, it has the potential to show antidiabetic activities. Objectives: This study was aimed to evaluate the impacts of Hibiscus esculentus extract on glucose and lipid profile of diabetic rats. The flavonoid, flavonol and phenolic components, as well as antioxidant activity of Hibiscus esculentus was also evaluated. Materials and Methods: In a preclinical study, 40 male Wistar rats were designated into four 10-member groups, i.e., control, diabetic control, diabetic Hibiscus esculentus, and diabetic glibenclamide. The Alloxan-induced diabetic rats received extracts orally for four weeks. Then, the serum biochemical factors were measured and compared by analysis of variance (ANOVA). Results: Serum glucose, triglyceride (TG), cholesterol, and low density lipoprotein cholesterol (LDL-C) were significantly decreased and high density lipoprotein cholesterol (HDL-C) increased in diabetic Hibiscus esculentus rats compared to diabetic control ones (P < 0.05). Conclusion: Improving the blood glucose and lipid profile in diabetic rats indicates that Hibiscus esculentus extract might be beneficial in diabetic patients.

(3) Martellucci J, Rossi G, Corsale I, Carrieri P, D'Elia M, Giani I. Myoxinol ointment for the treatment of acute fissure. Updates Surg. 2017 Dec;69(4):499-503. doi: 10.1007/s13304-017-0450-z. 

Abstract. Myoxinol is a complex of oligopeptides obtained from the seeds of Hibiscus esculentus used in cosmetic as natural alternative to botulin toxin. The aim of the study was to evaluate the safety and effectiveness of local myoxinol for the treatment of acute anal fissure. All the consecutive patients with acute fissure treated from January to June 2014 underwent 30 days of topical treatment (twice/day) with a mioxinol based ointment. Pain, symptomatic relief, fissure healing and re-epithelization, 1-year recurrence rate, subjective satisfaction and need for further treatments were evaluated. During the study period 157 patients were eligible for data analysis (91 males: 58%; mean age 38 years: range 17-83). Median anal pain score was 7.1 pre-treatment and 1.7 and 0.9 after 30 days and 12 months from treatment, respectively (p: 0.0001). After the treatment period complete healing was achieved in 103 patients (65.5%), relevant improvement in 31 (20%) and no improvement in 21 patients (13.5%). Overall efficacy rate was 85.5%. A significant difference was reported considering patients with pre-treatment VAS between 1-5 and 6-10 (p: 0.004). Twenty-nine patients (18.5%) required further treatments. Hydrolyzed Hibiscus esculentus extract was proven to be an effective and well-tolerated topical treatment for acute fissure, with a high healing rate, a significant reduction of pain and a low 1-year recurrence rate.

(4) Alqasoumi SI. 'Okra' Hibiscus esculentus L.: A study of its hepatoprotective activity. Saudi Pharm J. 2012 Apr;20(2):135-41. doi: 10.1016/j.jsps.2011.10.002.

Abstract. In the present study, an attempt has been made to validate the claimed uses of 'Okra' Hibiscus esculentus in liver diseases. The preventive action of ethanolic extract of okra (EEO) against liver injury was evaluated in rodents using carbon tetrachloride-induced hepatotoxicity model. EEO, at 250 and 500 mg/kg body weight, exerted significant dose-dependent hepatoprotection by decreasing the CCl4-induced elevation of serum SGOT, SGPT, ALP, GGT, cholesterol, triglycerides and malondialdehyde (MDA) non-protein sulfhydryls (NP-SH) and total protein (TP) levels in the liver tissue. A significant reduction was also observed in pentobarbital-induced sleeping time in mice. The hepatoprotective and antioxidant activities of the extract are being comparable to standard silymarin. These findings were supported by histological assessment of the liver biopsy. The ability of okra extract to protect chemically induced liver damage may be attributed to its potent antioxidant property.