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Vanillin
"Vanillin studies"
by A_Partyns (12876 pt)
2019-May-15 17:37

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In addition to its industrial and food application, vanillin has an antimicrobial activity (1), a reduction effect of the biological mutation (2) and an antitumor action (3).

Vanillin is usually used as a chemical substitute for the taste of vanilla in food for economic reasons, but in the medical field, at established dosages, it acts as a liver protector in subjects (experiments on rats) chronically exposed to Potassium Bromate KBrO3 (4).

It is commonly used as a chemical flavor in cigarettes (5).

Other studies on vanillin (6).

References_______________________________________________

(1) Rakchoy S., Suppakul P., Jinkarn T. Antimicrobial effects of vanillin coated solution for coating paper board intended for packaging bakery products. Asian Journal of Food & Agro-industry. 2009;2(4):138–147.

(2) Imanishi H., Sasaki Y., Matsumoto K., et al. Suppression of 6-TG-resistant mutations in V79 cells and recessive spot formations in mice by vanillin. Mutation Research Letters. 1990;243(2):151–158. doi: 10.1016/0165-7992(90)90038-l.

(3) Ho K., Yazan L. S., Ismail N., Ismail M. Apoptosis and cell cycle arrest of human colorectal cancer cell line HT-29 induced by vanillin. Cancer Epidemiology. 2009;33(2):155–160. doi: 10.1016/j.canep.2009.06.003.

(4) Altered hepatic mRNA expression of immune response-associated DNA damage in mice liver induced by potassium bromate: Protective role of vanillin.
Ben Saad H, Driss D, Ben Amara I, Boudawara O, Boudawara T, Ellouz Chaabouni S, Mounir Zeghal K, Hakim A.
Environ Toxicol. 2015 Aug 21. doi: 10.1002/tox.22181.

(5) Flavour chemicals in electronic cigarette fluids.
Tierney PA, Karpinski CD, Brown JE, Luo W, Pankow JF.
Tob Control. 2016 Apr;25(e1):e10-5. doi: 10.1136/tobaccocontrol-2014-052175.

(6) Effect of vanillin on lipid profile in a model of hyperlipidemia, a preliminary study.
Belagali Y, Ullal SD, Shoeb A, Bhagwath V, Ramya K, Maskeri R.
Indian J Exp Biol. 2013 Apr;51(4):288-91.

Vanillin protects human keratinocyte stem cells against ultraviolet B irradiation.
Lee J, Cho JY, Lee SY, Lee KW, Lee J, Song JY.
Food Chem Toxicol. 2014 Jan;63:30-7. doi: 10.1016/j.fct.2013.10.031. Epub 2013 Oct 30.

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