A Novel Synthetic Compound, Bismuth Zinc Citrate, Could Potentially Reduce Cisplatin-Induced Toxicity Without Compromising the Anticancer Effect Through Enhanced Expression of Antioxidant Protein.
Chan S, Wang R, Man K, Nicholls J, Li H, Sun H, Chan GC.
Transl Oncol. 2019 May;12(5):788-799. doi: 10.1016/j.tranon.2019.02.003.

Zinc citrate incorporation with whey protein nanoparticles alleviate the oxidative stress complication and modulate gene expression in the liver of rats.
Hassan MA, El-Nekeety AA, Abdel-Aziem SH, Hassan NS, Abdel-Wahhab MA.
Food Chem Toxicol. 2019 Mar;125:439-451. doi: 10.1016/j.fct.2019.01.026.

First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease.
DeGrado TR, Kemp BJ, Pandey MK, Jiang H, Gunderson TM, Linscheid LR, Woodwick AR, McConnell DM, Fletcher JG, Johnson GB, Petersen RC, Knopman DS, Lowe VJ.
Mol Imaging. 2016 Dec 9;15. pii: 1536012116673793.

New toothpaste to deal with dentine hypersensitivity: double-blind randomized controlled clinical trial.
Katanec T, Majstorovic M, Negovetic Vranic D, Ivic Kardum M, Marks LA.
Int J Dent Hyg. 2018 Feb;16(1):78-84. doi: 10.1111/idh.12231.

Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide.
Wegmüller R, Tay F, Zeder C, Brnic M, Hurrell RF.
J Nutr. 2014 Feb;144(2):132-6. doi: 10.3945/jn.113.181487.

Zinc citrate  is a chemical compound, inorganic salt of citric acid (α and β-hydroxytricarboxylic acid). 

The industrial production of citric acid takes place by mycological fermentation of raw sugar from Aspergillus niger and subsequent crystallisation with alkaline solutions.

It appears as white powder.

Zinc in the human body constitutes an important immunological barrier and its deficiency can lead to diseases of the skin, bones and sight.

What it is used for and where

Cosmetics

Antimicrobial agent. This ingredient is able to suppress or inhibit the growth and replication of a broad spectrum of microorganisms such as bacteria, fungi and viruses by making the stratum corneum temporarily bactericidal and fungicidal.

Oral care agent. This ingredient can be placed in the oral cavity to improve and/or maintain oral hygiene and health, to prevent or improve a disorder of the teeth, gums, mucous membrane.

Anti-caries agent. This ingredient has the property of preventing the onset of caries by fighting the bacteria responsible for acid corrosion of teeth.

Zinc citrate studies

Molecular Formula: C₁₂H₁₀O₁₄Zn₃

Molecular Weight: 574.338 g/mol

UNII: K72I3DEX9B

CAS: 546-46-3  12405-10-6  25618-84-2

EC Number: 208-901-2

FEMA Number:

Synonyms:

• Trizinc dicitrate
• 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, zinc salt (2:3)
• Citric acid, zinc salt
• trizinc 2-hydroxypropane-1,2,3-tricarboxylate
• 2-Hydroxy-1,2,3-propanetricarboxylic acid, zinc salt
• 2-Hydroxy-1,2,3-propanetricarboxylic acid zinc salt
• 8b-hydroxy-4aH-eudesm-5-en-12-oic acid
• trizinc 2-oxidanylpropane-1,2,3-tricarboxylate
• [3aR-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho-[2,3-b]furan-2(3H)-one