Scant scientific literature on the safety of this CI 74260 dye, a copper-phthalocyanine compound used as a pigment in cosmetic products.

A single case of allergic contact dermatitis, but not to this specific product, but to a similar copper-phthalocyanine dye (1).

Other studies

Pyrolysis gas chromatography mass spectrometry of two green phthalocyanine pigments and their identification in paint systems  Giulia Germinario, Inez Dorothé van der Werf, Luigia Sabbatini  Journal of Analytical and Applied Pyrolysis  Volume 115, September 2015, Pages 175-183  https://doi.org/10.1016/j.jaap.2015.07.016

The photodynamic effect of far-red range phthalocyanines (AlPc and Pc green) supported by electropermeabilization in human gastric adenocarcinoma cells of sensitive and resistant type.  Zielichowska A, Saczko J, Garbiec A, Dubińska-Magiera M, Rossowska J, Surowiak P, Choromańska A, Daczewska M, Kulbacka J, Lage H.  Biomed Pharmacother. 2015 Feb;69:145-52. doi: 10.1016/j.biopha.2014.11.017.

Concentration levels and congener profiles of polychlorinated biphenyls, pentachlorobenzene, and hexachlorobenzene in commercial pigments.  Anezaki K, Nakano T.  Environ Sci Pollut Res Int. 2014 Jan;21(2):998-1009. doi: 10.1007/s11356-013-1977-2

The origin of the halogen effect on the phthalocyanine green pigments.  Lee SU, Kim JC, Mizuseki H, Kawazoe Y.  Chem Asian J. 2010 Jun 1;5(6):1341-6. doi: 10.1002/asia.200900601.

Possible utilization of acrylic paint and copper phthalocyanine pigment sludge for vermiculture.  Majumdar D, Buch V, Macwan P, Patel J.  Waste Manag Res. 2010 May;28(5):423-9. doi: 10.1177/0734242X09351898.

References__________________________

(1) Allergic contact dermatitis caused by the blue pigment VINAMON® Blue BX FW - a phthalocyanine blue in a vinyl glove.
Weimann S, Skudlik C, John SM. - J Dtsch Dermatol Ges. 2010 Oct

CI 74260 is a chemical compound, an organic green pigment.

It is a dye composed of copper and phthalocyanine and is commonly called by the name of Pigment Green 7 or green phthalocyanine. The green phthalocyanine pigment (PG7) is thermally stable and degradation begins only after 550° C (1).

The name defines the structure of the molecule:

• "Phthalocyanine" refers to the complex organic compound that forms the basis of this and many other pigments. Phthalocyanins are large planar structures similar to porphyrins in heme and chlorophyll. They consist of four isoindole units connected by nitrogen atoms to form a large, cyclic conjugate system that absorbs visible light.
• "Green" refers to the color of the pigment, which is a bright, intense green.

The synthesis process takes place in several stages:

• Step 1: Preparation of raw materials: phthalthionitrile and a suitable metal salt.
• Step 2: Cyclotetramerization. In the presence of metallic salt, phthiltitrile undergoes a cyclotetramerization reaction that forms the ring structure of phthalocyanin.
• Step 3: Replacement. The resulting phthalocyanine undergoes a substitution reaction to introduce the substituents necessary to give Phthalocyanine Green its characteristic color.
• Step 4: Purification. The resulting Phthalocyanine Green is purified to remove any unreacted starting materials and by-products with a series of washing and filtration steps.
• Step 5: Drying. Green purified phthalocyanin is then dried to remove any residual solvent.

What it is for and where

Cosmetics

It is a restricted ingredient as  IV/107 a Relevant Item in the Annexes of the European Cosmetics Regulation 1223/2009 regulated by 88/667/EEC.

Colorant. This ingredient has the function of colouring the solution in which it is inserted in a temporary, semi-permanent or permanent manner, either alone or in the presence of the complementary components added for colouring.

Safety. It is an ingredient that has some important contraindications regarding the health profile: it should not enter areas close to the eyes.

The most relevant studies on this chemical compound have been selected with a summary of their contents:

CI 74260 Studies

• Molecular formula: C₃₂Cl₁₆CuN₈     C₃₂HCl₁₅N₈.Cu
• Molecular weight: 1127.19
• CAS: 1328-53-6 14832-14-5
• UNII   BPO9294G4W
• EC number    215-524-7

Synonyms:

• PHTHALOCYANINE GREEN
• PHTHALOCYANINE GREEN G
• PIGMENT GREEN 7
• n31,n32]-n3(sp-4-1)-locyaninato(2-)-n2
• pigmentgreen
• 7 PIGMENT GREEN 7
• Copper, 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-hexadecachloro-29H,31H-phthalocyaninato(2-)-.kappa.N29,.kappa.N30,.kappa.N31,.kappa.N32-, (SP-4-1)-
• copper perchlorophthalocyanine
• [1,2,3,4,8,9,10,11,15,16,17, 18, 22,23,24,25-hexadecachloro-29H,31H-phthalocyaninato-N29,N30,N3Copper
• Copper,[1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-hexadecachloro-29H,31H-phthalocyaninato-N29,N30,N31,N32]-,(SP-4-1)-
• Copper, [1,2,3,4,8,9,10,11,15,16, 17,18,22,23,24,25-hexadecachloro-29H,31H-phthalocyaninato (2-)-N29,N30,N31,N32]-, (SP-4-1)-
• [1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-hexadecachloro-29H,31H-phthalocyaninato(2-)-N29,N30,N3Copper
• copper,[1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-hexadecachloro-29h,31h-phtha

References_____________________________________________

(1) La Nasa J, Lee J, Degano I, Burnstock A, van den Berg KJ, Ormsby B, Bonaduce I. The role of the polymeric network in the water sensitivity of modern oil paints.   Sci Rep. 2019 Mar 5;9(1):3467. doi: 10.1038/s41598-019-39963-z.