CI 73360 is a chemical compound, also known as Red 30 or D&C Red 30, is a red pigment used in cosmetics, personal care products, and some pharmaceutical products to impart color.
It is classed chemically as a thioindigoid colour.
The name describes the structure of the molecule
- The CI (Color Index) numbering is a standardized system for classifying dyes.
- "73360" is the specific number assigned to this particular red pigment.
Description of raw materials used in production
The exact composition and raw materials for producing CI 73360 may vary depending on specific production methods and companies. However, the production of organic pigments like CI 73360 often involves aromatic precursors and conducting chemical reactions to form the dye structure.
Synthesis process
The specific synthesis of CI 73360 is not available to the public due to industrial patents or trade secrets. However, the production of similar pigments often involves chemical reactions between aromatic precursors, followed by purification, grinding, and treatment processes to yield the final product.
What it is for and where
Cosmetics
It is a restricted ingredient as IV/100 a Relevant Item in the Annexes of the European Cosmetics Regulation 1223/2009. Substance or ingredient reported: 6-Chloro-2-(6-chloro-4-methyl-3-oxobenzo[b]thien-2(3H)-ylidene)-4-methylbenzo[b]thiophene-3(2H)-one
Cosmetics - Used as a coloring agent in various cosmetic products such as lipsticks, blushes, eyeshadows, and nail polishes.
Personal Care Products - Can be found in products like shampoos, body washes, and other body and hair care products where coloring is desired.
Pharmaceutical Products - Sometimes used to color pills and capsules to make them easily identifiable.
Safety
An impurity has been identified in the dye D&C Red 30 (1), it will be necessary to check over time if the production process has been modified to remove the impurity.
- Molecular formula: C18H10Cl2O2S2
- Molecular weight: 393.31 g / mol
- CAS: 2379-74-0
- EINECS 219-163-6
- UNII 2S42T2808B
- DTXSID601045209
Synonyms:
- Pigment Red 181
- Pigment Yellow 181
- (delta,(sup2,2’(3h,3’h))-bibenzo(b)thiophene)-3,3’-dione,6,6’-dichloro-4,4’
- (2E)-6-chloro-2-(6-chloro-4-methyl-3-oxo-1-benzothiophen-2-ylidene)-4-methyl-1-benzothiophen-3-one
- Vat red 1
- Daltolite Pink FF
- Helindon Pink R
- Durindone Pink FF
- Fenidon Pink R
- Helindone Pink CN
- Indanthren Brilliant Pink R
- Calophyl Pink ZFF
- Fast Pink Y
- Helanthrene Pink R
- Ciba Pink FF
- Vat Pink FF
- Helindone Pink CN
- Amanthrene Pink FF
References_____________________________________________________________________
(1) Weisz A, Perez-Gonzalez M, Wood JF, Ridge CD, Ito Y. Identification, separation by spiral high-speed counter-current chromatography, and quantification of 7-chloro-5-methyl-2H-1,4-benzothiazin-3(4H)-one, an impurity in the thioindigoid color additive D&C Red No. 30 and its lakes. J Chromatogr A. 2021 Jan 25;1637:461863. doi: 10.1016/j.chroma.2020.461863.
Abstract. An impurity in the color additives D&C Red No. 30 (R30) and D&C Red No. 30 lakes (R30L) was newly identified and characterized as 7-chloro-5-methyl-2H-1,4-benzothiazin-3(4H)-one (BTZ), and its extent and level in certified batches of these color additives was determined. BTZ was extracted from the dye with ethanol, resulting in a crude extract enriched to a concentration of over 60%. BTZ was then separated from a portion of the enriched extract by high-speed counter-current chromatography using a spiral-tube assembly column with intermittently pressed tubing of 60 ml capacity. It was the first reported use of such a column to separate a small, moderately hydrophobic compound. The two-phase solvent system was also moderately hydrophobic, consisting of hexane-ethyl acetate-methanol-water (5:2:5:2), and the retention of the organic stationary phase measured after the separation was 83.3%. The separation yielded BTZ of two purity grades, the higher of which (~95.5%) was used as a standard to quantify the impurity in 37 batches of R30 and R30L using an HPLC method developed and validated for that purpose. Analyses revealed a wide range of BTZ levels across batches, <0.05 - 0.84%, and suggested that BTZ contamination could be reduced by appropriate adjustments in the manufacturing process. An explanation of the likely source of BTZ - as a side-reaction product in a particular step of the manufacturing process - was also presented.
CI 73360 
