Preclinical investigation of the cardiovascular actions induced by aqueous extract of Pimpinella anisum L. seeds in rats.
Pontes VCB, Rodrigues DP, Caetano A, Gamberini MT.
J Ethnopharmacol. 2019 Jun 12;237:74-80. doi: 10.1016/j.jep.2019.03.050

Antimicrobial activity of spices essential oils and its effectiveness on mature biofilms of human pathogens.
Condò C, Anacarso I, Sabia C, Iseppi R, Anfelli I, Forti L, de Niederhäusern S, Bondi M, Messi P.
Nat Prod Res. 2018 Oct 13:1-8. doi: 10.1080/14786419.2018.1490904.

Pimpinella anisum essential oil nanoemulsions against Tribolium castaneum-insecticidal activity and mode of action.
Hashem AS, Awadalla SS, Zayed GM, Maggi F, Benelli G.
Environ Sci Pollut Res Int. 2018 Jul;25(19):18802-18812. doi: 10.1007/s11356-018-2068-1.

Pimpinella anisum L. fruit: Chemical composition and effect on rat model of nonalcoholic fatty liver disease.
Asadollahpoor A, Abdollahi M, Rahimi R.
J Res Med Sci. 2017 Mar 15;22:37. doi: 10.4103/1735-1995.202147

Green synthesis of silver nanoparticles using Pimpinella anisum seeds: antimicrobial activity and cytotoxicity on human neonatal skin stromal cells and colon cancer cells.
Alsalhi MS, Devanesan S, Alfuraydi AA, Vishnubalaji R, Munusamy MA, Murugan K, Nicoletti M, Benelli G.
Int J Nanomedicine. 2016 Sep 6;11:4439-4449.

Phytochemical Profile and Evaluation of the Biological Activities of Essential Oils Derived from the Greek Aromatic Plant Species Ocimum basilicum, Mentha spicata, Pimpinella anisum and Fortunella margarita.
Fitsiou E, Mitropoulou G, Spyridopoulou K, Tiptiri-Kourpeti A, Vamvakias M, Bardouki H, Panayiotidis MΙ, Galanis A, Kourkoutas Y, Chlichlia K, Pappa A.
Molecules. 2016 Aug 16;21(8). pii: E1069. doi: 10.3390/molecules21081069.

What it is used for and where

• pharmaceutical
• feed

• eugenol
• estragole
• anisaldehyde
• methylchavicol

It should be borne in mind that when buying anise in a grocery store, it can be mixed with plant seeds of the same species, with different colors, but with similar taste and aroma.

Cosmetics

Skin conditioning agent. It is the mainstay of topical skin treatment by restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants.

Fragrance. It plays a very important role in the formulation of cosmetic products as it allows perfume to be enhanced, masked or added to the final product, improving its commercial viability.  The consumer always expects to find a pleasant scent in a cosmetic product.

Anise studies

References______________________________________________________________________

(1) Anti-microbial, cytotoxicity, and necrotic ripostes of Pimpinella anisum essential oil.  Abdel‐Reheem M. A. T., & Oraby M. M. (2015). https://doi.org/10.1016/j.aoas.2015.10.001