Tetramethylolglycoluril is a chemical compound.

Breakdown of the name and function of the components

• Tetramethylol - Indicates the presence of four methylol groups (i.e., -CH2OH groups) attached to the molecule.
• Glycoluril - A molecule derived from the fusion of glycol and urea.

Description and function of the raw materials used in production

• Glycoluril - Used as the base for the reaction.
• Formaldehyde - Reacts with glycoluril to form the methylol groups on the glycoluril molecule.

Summary of its industrial synthesis process step by step

• Preparation of the glycoluril solution - Glycoluril is dissolved in a suitable solvent.
• Addition of formaldehyde - Formaldehyde is added to the glycoluril solution.
• Heating - The mixture is heated to promote the formation of methylol groups on glycoluril.
• Cooling - After a certain period of time, the reaction is cooled down.
• Isolation of the product - Tetramethylol glycoluril precipitates or is separated from the mixture.
• Purification - Any impurities are removed using methods like filtration or crystallization.

What it is for and where

Cosmetics

Antimicrobial agent. This ingredient is able to suppress or inhibit the growth and replication of a broad spectrum of microorganisms such as bacteria, fungi and viruses by making the stratum corneum temporarily bactericidal and fungicidal.

Tetramethylol glycoluril is used by industry in cleaning products as a binder and preservative.

Tetramethylolglycoluril studies

• Molecular Formula: C₈H₁₄N₄O₆
• Molecular Weight: 262.222 g/mol
• UNII: 3BH30G5P9H
• CAS: 5395-50-6  53272-25-6  100091-50-7
• EC Number: 226-408-0
• FEMA Number:

Synonyms:

• Tetramethylol Acetylenediurea
• 1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione
• Tetramethylolglycoluril
• Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-
• Glycoluril, 1,3,4,6-tetrakis(hydroxymethyl)-
• Imidazo(4,5-d)imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-
• Glycoluril,3,4,6-tetrakis(hydroxymethyl)-
• N,N'',N'''-Tetrakis(hydroxymethyl)glycoluril
• Tetramethylol acetylene diurea
• Imidazo[4,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-
• N,N',N'',N'''-Tetrakis(hydroxymethyl)glycoluril
• 140
• Tetramethylol acetylene diuriene
• {Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione,} tetrahydro-1,3,4, 6-tetrakis(hydroxymethyl)-
• 1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo-[4,5-d]imidazole-2,5(1H,3H)-dione
• 1,3,4,6-Tetrakis-hydroxymethyl-tetrahydro-imidazo(4,5-d)imidazole-2,5-dione
• Tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo(4,5-d)imidazole-2,5(1H,3H)-dione
• 1,3,4,6-tetrakis(hydroxymethyl)-1,3,4,6,3a,6a-hexahydro-1,3,4,6-tetraazapental ene-2,5-dione
• Tetrakis(hydroxymethyl)glycoluril
• tetramethylol glycoluril
• 1,3,4,6-tetrakis(hydroxymethyl)-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione

Salkeeva, L. K., Shibaeva, A. K., Bakibaev, A. A., Taishibekova, E. K., Minaeva, E. V., Zhortarova, A. A., & Sal’keeva, A. K. (2014). New heterocycles based on tetramethylol glycoluril. Russian Journal of General Chemistry, 84, 338-339.

Kirsanov, V. Y., & Rakhimova, E. B. (2022). Recent Advances in the Chemistry of Saturated Annulated Nitrogen-Containing Polycyclic Compounds. International Journal of Molecular Sciences, 23(24), 15484.

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Carlson RM, Smith MC, Nedorost ST. Diagnosis and treatment of dermatitis due to formaldehyde resins in clothing. Dermatitis. 2004 Dec;15(4):169-75. Erratum in: Dermatitis. 2005 Jun;16(2):106. PMID: 15842060.

Scheman AJ, Carroll PA, Brown KH, Osburn AH. Formaldehyde-related textile allergy: an update. Contact Dermatitis. 1998 Jun;38(6):332-6. doi: 10.1111/j.1600-0536.1998.tb05769.x. PMID: 9687033.